Anti-angiogenic agents—overcoming tumour endothelial cell anergy and improving immunotherapy outcomes
ZR Huinen, EJM Huijbers, JR van Beijnum… - Nature Reviews …, 2021 - nature.com
Immune checkpoint inhibitors have revolutionized medical oncology, although currently only
a subset of patients has a response to such treatment. A compelling body of evidence …
a subset of patients has a response to such treatment. A compelling body of evidence …
[HTML][HTML] Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders
S Rana, SD Burke, SA Karumanchi - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …
The placenta in fetal growth restriction: what is going wrong?
The placenta is essential for the efficient delivery of nutrients and oxygen from mother to
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …
[HTML][HTML] Placental adaptations in growth restriction
The placenta is the primary interface between the fetus and mother and plays an important
role in maintaining fetal development and growth by facilitating the transfer of substrates and …
role in maintaining fetal development and growth by facilitating the transfer of substrates and …
[HTML][HTML] Regulation of vascular growth and function in the human placenta
During the course of 9 months, the human placenta develops into a highly vascular organ.
Vasculogenesis starts during the third week post-conception. Hemangioblastic cell cords …
Vasculogenesis starts during the third week post-conception. Hemangioblastic cell cords …
[HTML][HTML] MicroRNAs: crucial regulators of placental development
MicroRNAs (miRNAs) are small non-coding single-stranded RNAs that are integral to a wide
range of cellular processes mainly through the regulation of translation and mRNA stability …
range of cellular processes mainly through the regulation of translation and mRNA stability …
Vascular biology of the placenta
H Weiler - Endothelial Cells in Health and Disease, 2005 - taylorfrancis.com
The placenta is a gender-specific transitory organ with the sole purpose of enabling the
growth and development of the fetus. It mediates the efficient transfer and exchange of …
growth and development of the fetus. It mediates the efficient transfer and exchange of …
Placental formation in early pregnancy: how is the centre of the placenta made?
AL Boss, LW Chamley, JL James - Human reproduction update, 2018 - academic.oup.com
BACKGROUND Correct development of the placenta is critical to establishing pregnancy
and inadequate placentation leads to implantation failure and miscarriage, as well as later …
and inadequate placentation leads to implantation failure and miscarriage, as well as later …
[HTML][HTML] The impact of infection in pregnancy on placental vascular development and adverse birth outcomes
AM Weckman, M Ngai, J Wright, CR McDonald… - Frontiers in …, 2019 - frontiersin.org
Healthy fetal development is dependent on nutrient and oxygen transfer via the placenta.
Optimal growth and function of placental vasculature is therefore essential to support in …
Optimal growth and function of placental vasculature is therefore essential to support in …
[HTML][HTML] Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature
Progress in the understanding of the biology of perinatal tissues has contributed to the
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …