There is a growing body of literature that recognizes the positive effects of exercise on mood
states such as anxiety, stress and depression, through physiological and biochemical …

Alzheimer's disease (AD), a common neurodegenerative disease in the elderly and the most
prevalent cause of dementia, is characterized by progressive cognitive impairment. The …

BACKGROUND Neurons are polarized cells with extreme geometries. Multiple dendrites
and one axon generally emerge from a single cell body and establish synaptic contacts with …

Human and animal studies suggest an intriguing link between mitochondrial diseases and
depression. Although depression has historically been linked to alterations in …

It has been more than 100 years since Paul Ehrlich reported that various water-soluble dyes
injected into the circulation did not enter the brain. Since Ehrlich's first experiments, only a …

Background: Depression is the most debilitating neuropsychiatric disorder with significant
impact on socio-occupational and well being of individual. The exact pathophysiology of …

Neurons, perhaps more than any other cell type, depend on mitochondrial trafficking for their
survival. Recent studies have elucidated a motor/adaptor complex on the mitochondrial …

Mitochondria are essential organelles for neuronal growth, survival, and function. Neurons
use specialized mechanisms to drive mitochondria transport and to anchor them in axons …

The susceptibility of the brain to ischaemic injury dramatically limits its viability following
interruptions in blood flow. However, data from studies of dissociated cells, tissue …

Neurons and glia maintain central nervous system (CNS) homeostasis through diverse
mechanisms of intra-and intercellular signaling. Some of these interactions include the …