Dopamine is an important neurotransmitter that plays a critical role in motivational salience
and motor coordination. However, dysregulated dopamine metabolism can result in the …

Although it is generally accepted that free radicals are involved in the neurodegenerative
process occurring in the dopaminergic neurons of the nigro-striatal system in Parkinson's …

Parkinson's disease (PD) is a neurodegenerative disorder that progresses over time and is
characterized by preferential reduction of dopaminergic neurons in the substantia nigra …

Human glutathione transferase M2-2 prevents the formation of neurotoxic aminochrome and
dopachrome by catalyzing the conjugation of dopamine and dopa o-quinone with …

The purpose of this study was to evaluate the contribution of DT-diaphorase inhibition to in
vivo neurodegenerative effects of dopamine (DA) oxidation to the corresponding o …

The dopamine oxidation product cysteinyl-dopamine has attracted attention as a contributor
to the death of dopaminergic neurons in Parkinson's disease. Treatment of cysteinyl …

The subject invention pertains to tumor cell lines useful for increasing the proliferation
potential of any human or animal cell in culture, thereby providing immortalized or …

Methylenedioxymethamphetamine (MDMA) is a relatively selective dopaminergic neurotoxin
in mice. Previous studies demonstrated the participation of α-7 nicotinic receptors (nAChR) …

Dopamine (DA) and its metabolites have been implicated in the pathogenesis of Parkinson's
disease. DA can produce reactive‐oxygen species and DA‐derived quinones such as …

Porous silicon photoluminescence is characterized by a broad emission band that displays
unusually long (tens to hundreds of microseconds), wavelength-dependent emissive …