Animal chlamydioses and zoonotic implications

D Longbottom, LJ Coulter - Journal of comparative pathology, 2003 - Elsevier
Members of the family Chlamydiaceae are obligate intracellular gram-negative bacteria that
cause a broad spectrum of disease in man, other mammals and birds. Infection in animals …

Chlamydia trachomatis type III secretion: evidence for a functional apparatus during early‐cycle development

KA Fields, DJ Mead, CA Dooley… - Molecular …, 2003 - Wiley Online Library
The obligate intracellular bacterium Chlamydia trachomatis occupies a parasitophorous
vacuole termed an inclusion. During its intracellular developmental cycle, C. trachomatis …

Mechanism of C. trachomatis attachment to eukaryotic host cells

JP Zhang, RS Stephens - Cell, 1992 - cell.com
A novel trimolecular mechanism of microbial attachment to mammalian host cells was
characterized for the obligate intracellular pathogen Chlamydia trachomatis. Using purified …

Mammalian 14‐3‐3β associates with the Chlamydia trachomatis inclusion membrane via its interaction with IncG

MA Scidmore, T Hackstadt - Molecular microbiology, 2001 - Wiley Online Library
Chlamydiae replicate intracellularly within a vacuole that is modified early in infection to
become fusogenic with a subset of exocytic vesicles. We have recently identified four …

Vesicular interactions of the Chlamydia trachomatis inclusion are determined by chlamydial early protein synthesis rather than route of entry

MA Scidmore, DD Rockey, ER Fischer… - Infection and …, 1996 - Am Soc Microbiol
Chlamydiae replicate intracellularly within a vacuole that has recently been characterized as
intersecting an exocytic pathway. One of the initial events during chlamydial infection is the …

Histopathologic changes related to fibrotic oviduct occlusion after genital tract infection of mice with Chlamydia muridarum

AA Shah, JH Schripsema, MT Imtiaz… - Sexually transmitted …, 2005 - journals.lww.com
Objectives: We sought to determine if intraluminal occluding fibrosis of the oviduct occurs
after urogenital Chlamydia muridarum infection in mice. Study: Oviduct occlusion was …

Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism

KA Fields, T Hackstadt - Molecular microbiology, 2000 - Wiley Online Library
The medically significant, obligate intracellular pathogen Chlamydia trachomatis replicates
within vacuoles termed inclusions. A developmental cycle is initiated after entry into a host …

Identification and characterization of a Chlamydia trachomatis early operon encoding four novel inclusion membrane proteins

MA Scidmore‐Carlson, EI Shaw… - Molecular …, 1999 - Wiley Online Library
Chlamydia trachomatis is a bacterial obligate intracellular parasite that replicates within a
vacuole, termed an inclusion, that does not fuse with lysosomes. Within 2 h after …

[PDF][PDF] Inhibition of chlamydial infectious activity due to P2X7R-dependent phospholipase D activation

R Coutinho-Silva, L Stahl, MN Raymond, T Jungas… - Immunity, 2003 - cell.com
Chlamydia trachomatis survives within host cells by inhibiting fusion between Chlamydia
vacuoles and lysosomes. We show here that treatment of infected macrophages with ATP …

Trafficking from CD63-positive late endocytic multivesicular bodies is essential for intracellular development of Chlamydia trachomatis

WL Beatty - Journal of cell science, 2006 - journals.biologists.com
Chlamydiae are obligate intracellular bacterial pathogens that replicate solely within the
confines of a membrane-bound vacuole termed an inclusion. Within this protected organelle …