Objectives Lack of clarity on the definition of “patient engagement” has been highlighted as
a barrier to fully implementing patient engagement in research. This study identified themes …

Abstract Background Rare diseases (RDs) affect a small number of people within a
population. About 5000 to 8000 distinct RDs have been identified, with an estimated 6% to …

The current investigation aimed to manufacture and evaluate the structure–function
relationship of various 3D printed tablets by conjugating hot-melt extrusion (HME) and fused …

Background Patient engagement is an essential aspect in the research/development of
biopharmaceutical products and disease management. Improving the lives of patients …

The approach to patient engagement (PE) in drug development has changed rapidly due to
many factors, including the complexity of innovative drugs and the need to demonstrate …

Background Professional societies and other organizations have recently taken a visible
role trying to define treatment value via value frameworks and assessments, providing payer …

Background Regulators and clinical experts increasingly recognize the importance of
incorporating patient-reported outcomes (PROs) in clinical studies of therapies for …

Dravet syndrome (DS) is an intractable developmental and epileptic encephalopathy
significantly impacting affected children and their families. A novel, one-time, adeno …

Background There is increased recognition that incorporating patients' perspectives and
insights into the medicines development process results in better health outcomes and …

If a competent adult refuses medical treatment, physicians and public officials must respect
her decision. Coercive medical paternalism is a clear violation of the doctrine of informed …