Animal models of neurodegenerative disease: Recent advances in fly highlight innovative approaches to drug discovery
JA Tello, HE Williams, RM Eppler… - Frontiers in molecular …, 2022 - frontiersin.org
Neurodegenerative diseases represent a formidable challenge to global health. As
advances in other areas of medicine grant healthy living into later decades of life, aging …
advances in other areas of medicine grant healthy living into later decades of life, aging …
Repositioning of drugs for Parkinson's disease and pharmaceutical nanotechnology tools for their optimization
H Hernández-Parra, H Cortés… - Journal of …, 2022 - Springer
Parkinson's disease (PD) significantly affects patients' quality of life and represents a high
economic burden for health systems. Given the lack of safe and effective treatments for PD …
economic burden for health systems. Given the lack of safe and effective treatments for PD …
Repurposing immunomodulatory Imide Drugs (IMiDs) in neuropsychiatric and neurodegenerative disorders
YJ Jung, D Tweedie, MT Scerba, DS Kim… - Frontiers in …, 2021 - frontiersin.org
Neuroinflammation represents a common trait in the pathology and progression of the major
psychiatric and neurodegenerative disorders. Neuropsychiatric disorders have emerged as …
psychiatric and neurodegenerative disorders. Neuropsychiatric disorders have emerged as …
Evolving Landscape of Parkinson's Disease Research: Challenges and Perspectives
Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects
movement. It occurs due to a gradual deficit of dopamine-producing brain cells, particularly …
movement. It occurs due to a gradual deficit of dopamine-producing brain cells, particularly …
N-Adamantyl Phthalimidine: A New Thalidomide-like Drug That Lacks Cereblon Binding and Mitigates Neuronal and Synaptic Loss, Neuroinflammation, and …
SC Hsueh, W Luo, D Tweedie, DS Kim… - ACS Pharmacology & …, 2021 - ACS Publications
Neuroinflammation contributes to delayed secondary cell death following traumatic brain
injury (TBI), has the potential to chronically exacerbate the initial insult, and represents a …
injury (TBI), has the potential to chronically exacerbate the initial insult, and represents a …
Nutritional Quality, Techno-Functional Characteristics, and Safety of Biomass Powder and Protein Isolate Produced from Penicillium maximae
MAF Moura, VS Alves, JA Takahashi - Foods, 2022 - mdpi.com
This study investigated the suitability of Penicillium maximae biomass powder and protein
isolate as a food product or food ingredient. The biomass powder is rich in proteins (34.8%) …
isolate as a food product or food ingredient. The biomass powder is rich in proteins (34.8%) …
The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications
Originally believed to primarily affect neurons, Parkinson's disease (PD) has recently been
recognized to also affect the functions and integrity of microglia and astroglia, two cell …
recognized to also affect the functions and integrity of microglia and astroglia, two cell …
Drug repositioning for Parkinson's disease: an emphasis on artificial intelligence approaches
Parkinson's disease (PD) is one of the most incapacitating neurodegenerative diseases
(NDDs). PD is the second most common NDD worldwide which affects approximately 1 to 2 …
(NDDs). PD is the second most common NDD worldwide which affects approximately 1 to 2 …
Designing a rapid and selective electrochemical nanosensor based on molecularly imprinted polymer on the Fe3O4/MoS2/glassy carbon electrode for detection of …
M Afzali, A Mostafavi, Z Afzali, T Shamspur - Microchemical Journal, 2021 - Elsevier
Despite the importance and necessity of pomalidomide determination due to the dual activity
of it in vitro and in vivo, electrochemical methods have not been applied for this purpose, so …
of it in vitro and in vivo, electrochemical methods have not been applied for this purpose, so …
Repurposing pomalidomide as a neuroprotective drug: Efficacy in an alpha-synuclein-based model of parkinson's disease
MF Palmas, A Ena, C Burgaletto, MA Casu… - …, 2022 - Springer
Marketed drugs for Parkinson's disease (PD) treat disease motor symptoms but are
ineffective in stopping or slowing disease progression. In the quest of novel pharmacological …
ineffective in stopping or slowing disease progression. In the quest of novel pharmacological …