Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review
Background The cumulative effect of taking multiple medicines with anticholinergic
properties termed as anticholinergic burden can adversely impact cognition, physical …
properties termed as anticholinergic burden can adversely impact cognition, physical …
The cognitive impact of anticholinergics: a clinical review
N Campbell, M Boustani, T Limbil, C Ott… - … interventions in aging, 2009 - Taylor & Francis
Context The cognitive side effects of medications with anticholinergic activity have been
documented among older adults in a variety of clinical settings. However, there has been no …
documented among older adults in a variety of clinical settings. However, there has been no …
Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study
Importance Many medications have anticholinergic effects. In general, anticholinergic-
induced cognitive impairment is considered reversible on discontinuation of anticholinergic …
induced cognitive impairment is considered reversible on discontinuation of anticholinergic …
Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults
SL Risacher, BC McDonald, EF Tallman… - JAMA …, 2016 - jamanetwork.com
Importance The use of anticholinergic (AC) medication is linked to cognitive impairment and
an increased risk of dementia. To our knowledge, this is the first study to investigate the …
an increased risk of dementia. To our knowledge, this is the first study to investigate the …
The anticholinergic risk scale and anticholinergic adverse effects in older persons
JL Rudolph, MJ Salow, MC Angelini… - Archives of internal …, 2008 - jamanetwork.com
Background Adverse effects of anticholinergic medications may contribute to events such as
falls, delirium, and cognitive impairment in older patients. To further assess this risk, we …
falls, delirium, and cognitive impairment in older patients. To further assess this risk, we …
Anticholinergic activity of 107 medications commonly used by older adults
ML Chew, BH Mulsant, BG Pollock… - Journal of the …, 2008 - Wiley Online Library
The objective of this study was to measure the anticholinergic activity (AA) of medications
commonly used by older adults. A radioreceptor assay was used to investigate the AA of 107 …
commonly used by older adults. A radioreceptor assay was used to investigate the AA of 107 …
Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-city study
I Carrière, A Fourrier-Reglat, JF Dartigues… - Archives of internal …, 2009 - jamanetwork.com
Background Despite the high intake of medications with anticholinergic properties by
community-dwelling elderly persons, the effects on cognitive decline and dementia have …
community-dwelling elderly persons, the effects on cognitive decline and dementia have …
A systematic review of amnestic and non-amnestic mild cognitive impairment induced by anticholinergic, antihistamine, GABAergic and opioid drugs
C Tannenbaum, A Paquette, S Hilmer, J Holroyd-Leduc… - Drugs & aging, 2012 - Springer
Background Mild cognitive deficits are experienced by 18% of community-dwelling older
adults, many of whom do not progress to dementia. The effect of commonly used medication …
adults, many of whom do not progress to dementia. The effect of commonly used medication …
Anticholinergic drugs in geriatric psychopharmacology
J López-Álvarez, J Sevilla-Llewellyn-Jones… - Frontiers in …, 2019 - frontiersin.org
Drugs with anticholinergic action are widely prescribed in the elderly population due to their
potential clinical benefits. However, these benefits are limited by adverse effects which may …
potential clinical benefits. However, these benefits are limited by adverse effects which may …
Anticholinergic drugs and negative outcomes in the older population: from biological plausibility to clinical evidence
A Collamati, AM Martone, A Poscia, V Brandi… - Aging clinical and …, 2016 - Springer
The use of medication with anticholinergic properties is widespread among older subjects.
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …