Findings from epidemiological studies over the past 30 years have shown that visceral
adipose tissue, accurately measured by CT or MRI, is an independent risk marker of …

The prevalence of obesity has reached pandemic proportions worldwide and certainly in the
United States. Obesity is a well-established independent risk factor for development of many …

Obesity is recognized as a heterogeneous condition in which individuals with similar body
mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to …

Traditionally, peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a 91 kDa
transcription factor, regulates lipid metabolism and long-chain fatty acid oxidation by …

Epicardial adipose tissue is a unique and multifaceted fat depot with local and systemic
effects. This tissue is distinguished from other visceral fat depots by a number of anatomical …

Abstract Type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease
(CKD), are recognized among the most disruptive public health issues of the current century …

Aims Adipose tissue and inflammation may play a role in the pathophysiology of patients
with heart failure (HF) with mildly reduced or preserved ejection fraction. We therefore …

In recent years, brown adipose tissue (BAT) has been recognized not only as a main site of
non-shivering thermogenesis in mammals, but also as an endocrine organ. BAT secretes a …

Obesity-related cardiovascular disease in children is becoming more prevalent in
conjunction with the rise in childhood obesity. Children with obesity are predisposed to an …

Epicardial adipose tissue (EAT) is part of the visceral adipose tissue (VAT) that surrounds
the heart and it is a quantifiable, modifiable, and multifaceted tissue that has both local and …