Predominant ligament-centric soft-tissue involvement differentiates axial psoriatic arthritis from ankylosing spondylitis

D McGonagle, P David, T Macleod… - Nature Reviews …, 2023 - nature.com
Since the original description of spondyloarthritis 50 years ago, results have demonstrated
similarities and differences between ankylosing spondylitis (AS) and axial psoriatic arthritis …

Targeting toll-like receptor (TLR) pathways in inflammatory arthritis: two better than one?

S Santos-Sierra - Biomolecules, 2021 - mdpi.com
Inflammatory arthritis is a cluster of diseases caused by unregulated activity of the immune
system. The lost homeostasis is followed by the immune attack of one's self, what damages …

Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis

J Tang, S Mo, L Fan, S Fu, X Liu - Frontiers in Immunology, 2024 - frontiersin.org
Background Despite establishing an association between gut microbiota and
spondyloarthritis (SpA) subtypes, the causal relationship between them remains unclear …

[HTML][HTML] Shedding light on the role of ERAP1 in axial spondyloarthritis

MA Saad, AB Abdul-Sattar, IT Abdelal, A Baraka - Cureus, 2023 - ncbi.nlm.nih.gov
Spondyloarthritis (SpA) is a multifactorial chronic inflammatory disease affecting the axial
skeleton (axSpA) and/or peripheral joints (p-SpA) and entheses. The disease's …

Axial spondyloarthritis and diagnostic challenges: over-diagnosis, misdiagnosis, and under-diagnosis

M Bittar, MA Khan, M Magrey - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review This article aims to review the challenges in axial
spondyloarthritis diagnosis and identify the possible contributing factors. Recent Findings …

The role of aminopeptidase ERAP1 in human pathology—a review

L Țiburcă, DC Zaha, MC Jurca, E Severin… - Current Issues in …, 2024 - mdpi.com
Aminopeptidases are a group of enzymatic proteins crucial for protein digestion, catalyzing
the cleavage of amino acids at the N-terminus of peptides. Among them are ERAP1 (coding …

[HTML][HTML] Circular RNAs in peripheral blood mononuclear cells from ankylosing spondylitis

YP Tang, QB Zhang, F Dai, X Liao, ZR Dong… - Chinese medical …, 2021 - journals.lww.com
Background: Circular RNA (circRNA) is a type of closed circular noncoding RNA (ncRNA),
mostly formed by back-splicing or alternative splicing of pre-messenger RNA (mRNA). The …

Sex Bias in Diagnostic Delay: Are Axial Spondyloarthritis and Ankylosing Spondylitis Still Phantom Diseases in Women? A Systematic Review and Meta-Analysis

F Bandinelli, B Martinelli-Consumi, M Manetti… - Journal of Personalized …, 2024 - mdpi.com
Diagnostic delay (DD) is associated with poor radiological and quality of life outcomes in
axial spondyloarthritis (ax-SpA) and ankylosing spondylitis (AS). The female (F) population …

Advances of genomic medicine in psoriatic arthritis

CM Laborde, L Larzabal, Á González-Cantero… - Journal of Personalized …, 2022 - mdpi.com
Psoriatic arthritis (PsA) is a common type of inflammatory arthritis found in up to 40% of
patients with psoriasis. Although early diagnosis is important for reducing the risk of …

The role of HLA-B27 in Argentinian axial spondyloarthritis patients

R García-Salinas, S Ruta, JT Chichande… - JCR: Journal of Clinical …, 2022 - journals.lww.com
Background The prevalence of human leukocyte antigen B27 (HLA-B27) is variable around
the world. Our objectives were to estimate the frequency of HLA-B27 in an Argentinian …