Thiyl radicals have been used by nature in a broad range of biochemical processes. For
instance, thiol residues play an important role in many enzymatic processes as illustrated by …

In recent years, peptide-coupling reactions have significantly advanced in parallel with the
development of new peptidecoupling reagents, which have been covered in a number of …

Abstract Oxyma [ethyl 2‐cyano‐2‐(hydroxyimino) acetate] has been tested as an additive for
use in the carbodiimide approach for formation of peptide bonds. Its performance in relation …

We describe a new family of uronium‐type coupling reagents that differ in their iminium
moieties and leaving groups. The presence of the morpholino group in conjunction with an …

The second edition of this best-selling handbook is bigger, more comprehensive, and now
completely current. In addition to thorough updates to the discussions featured in the first …

Abstract N-Methoxy-N-methylamide, popularly addressed as the Weinreb amide, has
surfaced as an amide with a difference. This amide has served as an excellent acylating …

The activation of carboxylic acids for the formation of amides or esters is an important
process usually carried out using the so-called peptide coupling reagents.'The formation of …

Inter-and intramolecular additions of alkyl radicals, generated by SET photochemical
decarboxylation reactions of free carboxylic acids, to electron-deficient alkenes take place …

The stereocontrolled total synthesis of clavicipitic acid and aurantioclavine from a common
azepino [5, 4, 3-cd]-indole intermediate is reported. This key azepinoindole nucleus was …

Here we describe a new family of N-form immonium-type coupling reagents that differ in
their carbocation skeleton structure. The N-methylpiperazine derivative failed to form …