Biological potential of carbazole derivatives
A Głuszyńska - European journal of medicinal chemistry, 2015 - Elsevier
Carbazole skeleton is the key structural motif of many biologically active compounds
including synthetic and natural products. Over the past several years, a large number of …
including synthetic and natural products. Over the past several years, a large number of …
[HTML][HTML] Recent Developments and Biological Activities of N-Substituted Carbazole Derivatives: A Review
M Bashir, A Bano, AS Ijaz, BA Chaudhary - Molecules, 2015 - mdpi.com
Carbazoles represent an important class of heterocycles. These have been reported to
exhibit diverse biological activities such as antimicrobial, antitumor, antiepileptic …
exhibit diverse biological activities such as antimicrobial, antitumor, antiepileptic …
Recent advancement in the discovery and development of COX-2 inhibitors: Insight into biological activities and SAR studies (2008–2019)
Cyclooxygenase-2 is a very important physiological enzyme playing key roles in various
biological functions especially in the mechanism of pain and inflammation, among other …
biological functions especially in the mechanism of pain and inflammation, among other …
[HTML][HTML] Schiff's bases of quinazolinone derivatives: Synthesis and SAR studies of a novel series of potential anti-inflammatory and antioxidants
KP Rakesh, HM Manukumar, DC Gowda - Bioorganic & medicinal …, 2015 - Elsevier
A series of quinazolinone derived Schiff base derivatives 7–28 were synthesized and
characterized as novel antioxidants and anti-inflammatory agents. The in vitro antioxidant …
characterized as novel antioxidants and anti-inflammatory agents. The in vitro antioxidant …
Current progress on antioxidants incorporating the pyrazole core
VLM Silva, J Elguero, AMS Silva - European journal of medicinal chemistry, 2018 - Elsevier
The search of new antioxidants, as drugs candidates, is an active field of medicinal
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
chemistry. The synthesis of compounds with antioxidant potential has increased in recent …
Eco-friendly synthesis, characterization, in-silico ADMET and molecular docking analysis of novel carbazole derivatives as antibacterial and antifungal agents
In search of novel biologically potent compounds, three novel organic molecules have been
synthesized. The structures of the prepared compounds have been characterized by …
synthesized. The structures of the prepared compounds have been characterized by …
[HTML][HTML] Design, synthesis, X-ray crystal structures, anticancer, DNA binding, and molecular modelling studies of pyrazole–pyrazoline hybrid derivatives
We have designed and synthesized three pyrazole analogs (4, 5a, 5b), pyrazole-based
chalcones (6a–6d) and (8a–8h), and N-formyl/acetyl 1, 3, 5-trisubstituted pyrazoline analogs …
chalcones (6a–6d) and (8a–8h), and N-formyl/acetyl 1, 3, 5-trisubstituted pyrazoline analogs …
LNL-Carbazole Pincer Ligand: More than the Sum of Its Parts
G Kleinhans, AJ Karhu, H Boddaert, S Tanweer… - Chemical …, 2023 - ACS Publications
The utility of carbazole in photo-, electro-, and medicinal applications has ensured its
widespread use also as the backbone in tridentate pincer ligands. In this review, the aim is …
widespread use also as the backbone in tridentate pincer ligands. In this review, the aim is …
Design, synthesis, and SAR study of novel 4, 5-dihydropyrazole-Thiazole derivatives with anti-inflammatory activities for the treatment of sepsis
Z Zhang, P Cao, M Fang, T Zou, J Han, Y Duan… - European Journal of …, 2021 - Elsevier
Systemic inflammatory response syndrome is a major feature of sepsis which is one of the
major causes of death worldwide. It has been reported that 3, 5-diaryl-4, 5-dihydropyrazole …
major causes of death worldwide. It has been reported that 3, 5-diaryl-4, 5-dihydropyrazole …
Rational Design of Dipicolylamine-Containing Carbazole Amphiphiles Combined with Zn2+ as Potent Broad-Spectrum Antibacterial Agents with a Membrane …
J Liu, H Li, H Li, S Fang, J Shi, Y Chen… - Journal of Medicinal …, 2021 - ACS Publications
Antibiotic resistance has become one of the most urgently important problems facing
healthcare providers. A novel series of dipicolylamine-containing carbazole amphiphiles …
healthcare providers. A novel series of dipicolylamine-containing carbazole amphiphiles …