Application of radiation omics in the development of adverse outcome pathway networks: an example of radiation-induced cardiovascular disease

O Azimzadeh, S Moertl, R Ramadan… - … Journal of Radiation …, 2022 - Taylor & Francis
Background Epidemiological studies have indicated that exposure of the heart to doses of
ionizing radiation as low as 0.5 Gy increases the risk of cardiac morbidity and mortality with …

Individual response of the ocular lens to ionizing radiation

SGR Barnard, N Hamada - International Journal of Radiation …, 2023 - Taylor & Francis
Purpose Cataract (opacification of the ocular lens) is a typical tissue reaction (deterministic
effect) following ionizing radiation exposure, for which prevention dose limits have been …

Noncancer effects of ionizing radiation exposure on the eye, the circulatory system and beyond: Developments made since the 2011 ICRP Statement on Tissue …

N Hamada - Radiation Research, 2023 - meridian.allenpress.com
For radiation protection purposes, noncancer effects with a threshold-type dose-response
relationship have been classified as tissue reactions (formerly called nonstochastic or …

[HTML][HTML] A generalisation of the method of regression calibration

MP Little, N Hamada, LB Zablotska - Scientific Reports, 2023 - nature.com
There is direct evidence of risks at moderate and high levels of radiation dose for highly
radiogenic cancers such as leukaemia and thyroid cancer. For many cancer sites, however …

[HTML][HTML] A generalisation of the method of regression calibration and comparison with Bayesian and frequentist model averaging methods

MP Little, N Hamada, LB Zablotska - Scientific Reports, 2024 - nature.com
For many cancer sites low-dose risks are not known and must be extrapolated from those
observed in groups exposed at much higher levels of dose. Measurement error can …

The evidence for excess risk of cancer and non-cancer disease at low doses and dose rates

SL Simon, GM Kendall, SD Bouffler… - Radiation …, 2022 - meridian.allenpress.com
The question of whether there are excess radiation-associated health risks at low dose is
controversial. We present evidence of excess cancer risks in a number of (largely …

Age effects on radiation response: Summary of a recent symposium and future perspectives

MP Little, AV Brenner, EJ Grant… - … journal of radiation …, 2022 - Taylor & Francis
One of the principal uncertainties when estimating population risk of late effects from
epidemiological data is that few radiation-exposed cohorts have been followed up to …

Low-dose extrapolation factors implied by mortality and incidence data from the Japanese atomic bomb survivor Life Span study data

MP Little, N Hamada - Radiation research, 2022 - meridian.allenpress.com
Assessment of the effect of low dose and low-dose-rate exposure depends critically on
extrapolation from groups exposed at high dose and high-dose rates such as the Japanese …

[HTML][HTML] Involvement of GSTP1 in low dose radiation-induced apoptosis in GM12878 cells

J Cui, L Li, S Wei, Y Wei, Y Gong, H Yan, Y Yu… - Ecotoxicology and …, 2024 - Elsevier
Background Low-dose ionizing radiation-induced protection and damage are of great
significance among radiation workers. We aimed to study the role of glutathione S …

Review of recent impacts of artificial intelligence for radiation therapy procedures

FA Abolaban - Radiation Physics and Chemistry, 2023 - Elsevier
Artificial intelligence (AI) is a discipline of computing science whose goal is to develop
intelligent computer-based systems replicating humans' decision-making and problem …