Hydrogels for RNA delivery

R Zhong, S Talebian, BB Mendes, G Wallace… - Nature materials, 2023 - nature.com
RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …

Supramolecular adhesive hydrogels for tissue engineering applications

Y Zhao, S Song, X Ren, J Zhang, Q Lin… - Chemical …, 2022 - ACS Publications
Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …

[HTML][HTML] The application of hyaluronic acid in bone regeneration

P Zhai, X Peng, B Li, Y Liu, H Sun, X Li - International journal of biological …, 2020 - Elsevier
Hyaluronic acid (HA) exists naturally as an important component of the extracellular matrix
(ECM) in the human body. In recent decades, HA has been widely used in bone …

Bioinspired Spatiotemporal Management toward RNA Therapies

Y Ma, S Li, X Lin, Y Chen - ACS nano, 2023 - ACS Publications
Ribonucleic acid (RNA)-based therapies have become an attractive topic in disease
intervention, especially with some that have been approved by the FDA such as the mRNA …

Injection of microporous annealing particle (MAP) hydrogels in the stroke cavity reduces gliosis and inflammation and promotes NPC migration to the lesion

LR Nih, E Sideris, ST Carmichael… - Advanced …, 2017 - Wiley Online Library
With the number of deaths due to stroke decreasing, more individuals are forced to live with
crippling disability resulting from the stroke. To date, no therapeutics exist after the first 4.5 h …

Design of cell–matrix interactions in hyaluronic acid hydrogel scaffolds

J Lam, NF Truong, T Segura - Acta biomaterialia, 2014 - Elsevier
The design of hyaluronic acid (HA)-based hydrogel scaffolds to elicit highly controlled and
tunable cell response and behavior is a major field of interest in developing tissue …

Biomaterials for craniofacial bone regeneration

G Thrivikraman, A Athirasala, C Twohig… - Dental …, 2017 - dental.theclinics.com
Craniofacial bone regeneration has experienced tremendous expansion since the inception
of the concept of tissue engineering 1 more than two decades ago. Research and …

Biomimetic hydrogel containing copper sulfide nanoparticles and deferoxamine for photothermal therapy of infected diabetic wounds

H Shen, C Zhang, Y Meng, Y Qiao, Y Ma… - Advanced …, 2024 - Wiley Online Library
Inducing cell migration from the edges to the center of a wound, promoting angiogenesis,
and controlling bacterial infection are very important for diabetic wound healing …

Non-viral gene delivery systems for tissue repair and regeneration

P Wu, H Chen, R Jin, T Weng, JK Ho, C You… - Journal of translational …, 2018 - Springer
Critical tissue defects frequently result from trauma, burns, chronic wounds and/or surgery.
The ideal treatment for such tissue loss is autografting, but donor sites are often limited …

Porous hyaluronic acid hydrogels for localized nonviral DNA delivery in a diabetic wound healing model

T Tokatlian, C Cam, T Segura - Advanced healthcare materials, 2015 - Wiley Online Library
The treatment of impaired wounds requires the use of biomaterials that can provide
mechanical and biological queues to the surrounding environment to promote …