[HTML][HTML] The mechanisms of pharmacokinetic food-drug interactions–A perspective from the UNGAP group

M Koziolek, S Alcaro, P Augustijns, AW Basit… - European Journal of …, 2019 - Elsevier
The simultaneous intake of food and drugs can have a strong impact on drug release,
absorption, distribution, metabolism and/or elimination and consequently, on the efficacy …

[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs

X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

Gut microbiota, host organism, and diet trialogue in diabetes and obesity

V Lazar, LM Ditu, GG Pircalabioru, A Picu… - Frontiers in …, 2019 - frontiersin.org
The gastrointestinal tract with its microbiota is a complex, open, and integrated ecosystem
with a high environmental exposure. It is widely accepted that the healthy gut microbiotais …

Experimental diabetes induced by alloxan and streptozotocin: The current state of the art

M Radenković, M Stojanović, M Prostran - Journal of pharmacological and …, 2016 - Elsevier
Diabetes mellitus is a chronic metabolic disorder with a high prevalence worldwide. Animal
models of diabetes represent an important tool in diabetes investigation that helps us to …

Safety of probiotics: functional fruit beverages and nutraceuticals

I Žuntar, Z Petric, D Bursać Kovačević, P Putnik - Foods, 2020 - mdpi.com
Over the last decade, fruit juice consumption has increased. Their rise in popularity can be
attributed to the belief that they are a quick way to consuming a dietary portion of fruit …

[HTML][HTML] Effect of probiotics on glucose metabolism in patients with type 2 diabetes mellitus: A meta-analysis of randomized controlled trials

Q Zhang, Y Wu, X Fei - Medicina, 2016 - Elsevier
Objective Our aim was to investigate the effects of probiotics on glucose metabolism in
patients with type 2 diabetes mellitus using a meta-analysis of randomized, controlled trials …

Cardiovascular benefits of probiotics: a review of experimental and clinical studies

RM Thushara, S Gangadaran, Z Solati… - Food & function, 2016 - pubs.rsc.org
The microbiota inhabiting the human gastro-intestinal tract is reported to have a significant
impact on the health of an individual. Recent findings suggest that the microbial imbalance …

[HTML][HTML] Exploring the potential impact of probiotic use on drug metabolism and efficacy

C Purdel, A Ungurianu, I Adam-Dima… - Biomedicine & …, 2023 - Elsevier
Probiotics are frequently consumed as functional food and widely used as dietary
supplements, but are also recommended in treating or preventing various gastrointestinal …

Probiotics as potential biotherapeutics in the management of type 2 diabetes–prospects and perspectives

H Panwar, HM Rashmi, VK Batish… - … research and reviews, 2013 - Wiley Online Library
Diabetes mellitus is a looming epidemic worldwide, affecting almost all major sections of
society, creating burdens on global health and economy. A large number of studies have …

Probiotics supplementation improves hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes mellitus: An update of meta-analysis

T Liang, L Wu, Y Xi, Y Li, X Xie, C Fan… - Critical reviews in …, 2021 - Taylor & Francis
Background: Although many studies have shown that consumption of probiotics is relevant
to diabetes, the effects of probiotics improves clinical outcomes in type 2 diabetes have …