As the most common form of epigenetic regulation by RNA, N6 methyladenosine (m6A)
modification is closely involved in physiological processes, such as growth and …

Glioma is the most common primary tumor of the central nervous system (CNS).
Glioblastoma (GBM) is incurable with current treatment strategies. Additionally, the treatment …

Parkinson's disease (PD) is characterized by dopaminergic neurons degeneration in the
substantia nigra pars compacta. Increasing evidence indicates that peripheral CD4+ T cells …

Macrophages conduct critical roles in heart repair, but the niche required to nurture and
anchor them is poorly studied. Here, we investigated the macrophage niche in the …

HNRNPA2B1 is a member of the HNRNP family, which is associated with telomere function,
mRNA translation, and splicing, and plays an important role in tumor development. To date …

Although angiogenesis critically influences the progression of solid tumors, its contribution to
highly malignant, grade 4 diffuse gliomas remains unclear. After analyzing 506 …

Purpose Immune checkpoint blockade agents were shown to provide a survival advantage
in urothelial carcinoma, while some patients got minimal benefit or side effects. Therefore …

Glioma is the most common and aggressive type of primary malignant brain tumor. The N6-
methyladenosine (m6A) modification widely exists in eukaryotic cells and plays an important …

Background Lung adenocarcinoma (LUAD) is a common lung cancer with a poor prognosis
under standard chemotherapy. Hypoxia is a crucial factor in the development of solid …

Despite a long history of research, neurodegenerative diseases and malignant brain tumor
gliomas are both considered incurable, facing challenges in the development of treatments …