A Bird's‐Eye View on Deep Eutectic Solvent‐Mediated Multicomponent Synthesis of N‐Heterocycles

L Kumar S, A Servesh, Y Kumar Sriwastav… - …, 2023 - Wiley Online Library
Multicomponent reactions are crucial for operating organic synthesis. In today's world,
chemists concentrate on greener methodologies that cater to rising environmental concerns …

Six‐Membered Aromatic Nitrogen Heterocyclic Anti‐Tumor Agents: Synthesis and Applications

J Li, A Gu, XM Nong, S Zhai, ZY Yue… - The Chemical …, 2023 - Wiley Online Library
Cancer stands as a serious malady, posing substantial risks to human well‐being and
survival. This underscores the paramount necessity to explore and investigate novel …

Pyridylmethyl Radicals for Enantioselective Alkene Hydroalkylation Using “Ene”-Reductases

SG Bender, TK Hyster - ACS Catalysis, 2023 - ACS Publications
Aromatic electron-deficient heterocycles, such as pyridines, are found in many biologically
relevant structures, including those with medicinal applications. Methods for their …

Novel deep eutectic solvent catalysed single-pot open flask synthesis of tetrasubstituted-1H-pyrroles

SL Kumar, S Tabassum, S Govindaraju - Journal of Molecular Liquids, 2024 - Elsevier
Pyrrole and its analogs have garnered immense attention due to their multifaceted biological
significance and versatile applications, ranging from medicinal agents to fundamental …

NRF2 activation by nitrogen heterocycles: a review

MC Egbujor, P Tucci, UC Onyeije, CN Emeruwa… - Molecules, 2023 - mdpi.com
Several nitrogen heterocyclic analogues have been applied to clinical practice, and about
75% of drugs approved by the FDA contain at least a heterocyclic moiety. Thus, nitrogen …

Synergistic fabrication, characterization, and prospective optoelectronic applications of DES grafted activated charcoal dispersed PVA films

S Lokesh Kumar, CJ Binish, J Rajprasad… - Polymers for …, 2024 - Wiley Online Library
This study investigates the synthesis, analysis, and utility of films comprising deep eutectic
solvent (DES) grafted activated charcoal (AC) within a polyvinyl alcohol (PVA) matrix for …

Elevating pyrrole derivative synthesis: a three-component revolution

L Kumar S, A Servesh, SJ Chundattu, S Tabassum… - Molecular Diversity, 2024 - Springer
Pyrrole is an essential chemical with considerable relevance as a pharmaceutical
framework for many biologically necessary medications. The growing demand for …

[HTML][HTML] Mn2 (CO) 10 catalyzed visible-light-promoted synthesis of 1H-pyrazole-4-carboxamides; A sustainable multi-component statergy with antibacterial and …

S Govindaraju, SG Ramaraj, A Servesh… - Journal of …, 2024 - Elsevier
Multicomponent reactions play a pivotal role in synthesizing 1H-pyrazole-4-carboxamides,
underscoring its significance in sustainable organic synthesis. These compounds, valued for …

Transition‐Metal‐Free Synthesis of N‐Heterocyclic Compounds via Multi‐Component Reactions

DJ Boruah, L Borkotoky, UD Newar… - Asian Journal of …, 2023 - Wiley Online Library
Multicomponent reactions (MCRs) have emerged as powerful tools in synthetic chemistry for
the efficient synthesis of diverse molecular scaffolds, particularly nitrogen‐containing …

Design, synthesis and antimicrobial activities of novel bis-Mannich bases derived from lawsone

MR Khodabakhshi, A Adl, A Olyaei - Research on Chemical Intermediates, 2023 - Springer
A green and operationally simple approach for the library synthesis of novel bis-
heteroarylaminomethylnaphthoquinone derivatives by a one-pot pseudo five-component …