Chronic wounds

V Falanga, RR Isseroff, AM Soulika… - Nature Reviews …, 2022 - nature.com
Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …

Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds

H Zhao, J Huang, Y Li, X Lv, H Zhou, H Wang, Y Xu… - Biomaterials, 2020 - Elsevier
Bacterial infection has been a great threat to dermal wounds, especially to difficult-to-heal
diabetic wounds. It is known that reactive oxygen species (ROS) generated by wounds or …

[HTML][HTML] Challenges in exploring and manipulating the human skin microbiome

M Boxberger, V Cenizo, N Cassir, B La Scola - Microbiome, 2021 - Springer
The skin is the exterior interface of the human body with the environment. Despite its harsh
physical landscape, the skin is colonized by diverse commensal microbes. In this review, we …

[HTML][HTML] The human skin microbiome

AL Byrd, Y Belkaid, JA Segre - Nature Reviews Microbiology, 2018 - nature.com
Functioning as the exterior interface of the human body with the environment, skin acts as a
physical barrier to prevent the invasion of foreign pathogens while providing a home to the …

Chitosan/Hyaluronic acid/Alginate and an assorted polymers loaded with honey, plant, and marine compounds for progressive wound healing—Know-how

M Prasathkumar, S Sadhasivam - International journal of biological …, 2021 - Elsevier
Biomaterials are being extensively used in regenerative medicine including tissue
engineering applications, as these enhance tissue development, repair, and help in the …

Skin microbiota–host interactions

YE Chen, MA Fischbach, Y Belkaid - Nature, 2018 - nature.com
The skin is a complex and dynamic ecosystem that is inhabited by bacteria, archaea, fungi
and viruses. These microbes—collectively referred to as the skin microbiota—are …

[HTML][HTML] Biofilms in diabetic foot ulcers: Significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

Nanotechnology-driven therapeutic interventions in wound healing: potential uses and applications

S Hamdan, I Pastar, S Drakulich, E Dikici… - ACS central …, 2017 - ACS Publications
The chronic nature and associated complications of nonhealing wounds have led to the
emergence of nanotechnology-based therapies that aim at facilitating the healing process …

[HTML][HTML] Skin microbiota and its interplay with wound healing

M Tomic-Canic, JL Burgess, KE O'Neill, N Strbo… - American journal of …, 2020 - Springer
The skin microbiota is intimately coupled with cutaneous health and disease. Interactions
between commensal microbiota and the multiple cell types involved in cutaneous wound …