Vascular smooth muscle cells (VSMC s) exhibit phenotypic and functional plasticity in order
to respond to vascular injury. In case of the vessel damage, VSMC s are able to switch from …

538 Hypertension September 2018 or near normal LV ejection fractions, consistent with the
clinical picture of HFpEF. In the I-PRESERVE study (Irbesartan in Heart Failure With …

Noncoding RNAs (ncRNA) include a diverse range of functional RNA species—microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs) being most studied in pathophysiology …

Current knowledge on the renin–angiotensin system (RAS) indicates its central role in the
pathogenesis of cardiovascular remodelling via both hemodynamic alterations and direct …

The microbiome is a community of various microorganisms that inhabit or live on the skin of
humans/animals, sharing the body space with their hosts. It is a sort of complex ecosystem of …

Long intergenic non-coding RNA 00657 (linc00657) is involved in various diseases,
whereas its role in atherosclerosis (AS) development remains inconclusive. This study was …

Importance Mortality is high among patients heart failure (HF) who are receiving treatment,
and therefore identifying new pathways rooted in preclinical cardiac remodeling phenotypes …

Cardiovascular disease is the single largest cause of death in the western world and its
incidence is on the rise globally. Atherosclerosis, characterized by the development of …

Multiple factors underlie the pathophysiology of hypertension, involving endothelial
dysregulation, vascular smooth muscle dysfunction, increased oxidative stress, sympathetic …

COPD is a multifactorial disease caused by environmental determinants as well as genetic
risk factors. The prevalence and mortality of COPD continue to increase, and …