Real‐Time pH‐Dependent Self‐Assembly of Ionisable Lipids from COVID‐19 Vaccines and In Situ Nucleic Acid Complexation
Ionisable amino‐lipid is a key component in lipid nanoparticles (LNPs), which plays a crucial
role in the encapsulation of RNA molecules, allowing efficient cellular uptake and then …
role in the encapsulation of RNA molecules, allowing efficient cellular uptake and then …
Controlled self-assembly, isomerism, and guest uptake/release of charge-reversible lanthanide–organic octahedral cages
LP Zhou, XS Feng, SJ Hu, QF Sun - Journal of the American …, 2023 - ACS Publications
Charge plays a crucial role in the function of molecular and supramolecular systems, but
coordination hosts capable of orthogonal charge regulation remain elusive so far. In this …
coordination hosts capable of orthogonal charge regulation remain elusive so far. In this …
Systematic construction of progressively larger capsules from a fivefold linking pyrrole-based subcomponent
Biological encapsulants, such as viral capsids and ferritin protein cages, use many identical
subunits to tile the surface of a polyhedron. Inspired by these natural systems, synthetic …
subunits to tile the surface of a polyhedron. Inspired by these natural systems, synthetic …
Anionic Templates Drive Conversion between a ZnII9L6 Tricapped Trigonal Prism and ZnII6L4 Pseudo-Octahedra
HK Liu, TK Ronson, K Wu, D Luo… - Journal of the American …, 2023 - ACS Publications
This work introduces the use of 8-aminoquinoline subcomponents to generate complex
three-dimensional structures. Together with a tris (formylpyridine), 8-aminoquinoline …
three-dimensional structures. Together with a tris (formylpyridine), 8-aminoquinoline …
Solvent Drives Switching between Λ and Δ Metal Center Stereochemistry of M8L6 Cubic Cages
An enantiopure ligand with four bidentate metal-binding sites and four (S)-carbon
stereocenters self-assembles with octahedral ZnII or CoII to produce O-symmetric M8L6 …
stereocenters self-assembles with octahedral ZnII or CoII to produce O-symmetric M8L6 …
Cavity-Shape-Dependent Divergent Chemical Reaction inside Aqueous Pd6L4 Cages
Chemical reactions inside the confined pockets of enzyme-mimicking hosts, such as cages
and macrocycles, have been an emerging field of interest over the past decade. Although …
and macrocycles, have been an emerging field of interest over the past decade. Although …
54 K Spin Transition Temperature Shift in a Fe6L4 Octahedral Cage Induced by Optimal Fitted Multiple Guests
F Yin, J Yang, LP Zhou, X Meng, CB Tian… - Journal of the …, 2024 - ACS Publications
Spin-crossover (SCO) coordination cages are at the forefront of research for their potential in
crafting next-generation molecular devices. However, due to the scarcity of SCO hosts and …
crafting next-generation molecular devices. However, due to the scarcity of SCO hosts and …
Redox Triggers Guest Release and Uptake Across a Series of Azopyridine‐Based Metal–Organic Capsules
J Zheng, Y Yang, TK Ronson, DM Wood… - Advanced …, 2023 - Wiley Online Library
Precise control over guest release and recapture using external stimuli is a valuable goal,
potentially enabling new modes of chemical purification. Including redox moieties within the …
potentially enabling new modes of chemical purification. Including redox moieties within the …
Steric and Geometrical Frustration Generate Two Higher-Order CuI12L8 Assemblies from a Triaminotriptycene Subcomponent
The use of copper (I) in metal–organic assemblies leads readily to the formation of simple
grids and helicates, whereas higher-order structures require complex ligand designs. Here …
grids and helicates, whereas higher-order structures require complex ligand designs. Here …
Subtle Stereochemical Effects Influence Binding and Purification Abilities of an FeII4L4 Cage
A tetrahedral FeII4L4 cage assembled from the coordination of triangular chiral, face-
capping ligands to iron (II). This cage exists as two diastereomers in solution, which differ in …
capping ligands to iron (II). This cage exists as two diastereomers in solution, which differ in …