Atypical inflammatory demyelinating syndromes are rare disorders that differ from multiple
sclerosis owing to unusual clinical or MRI findings or poor response to treatments used for …

Tumefactive lesions are an uncommon manifestation of demyelinating disease and can
pose a diagnostic challenge in patients without a pre-existing diagnosis of multiple sclerosis …

Objective To describe demographic, clinical, and radiographic features of tumefactive
demyelination (TD) and identify factors associated with severe attacks and poor outcomes …

Acute disseminated encephalomyelitis is an immune-mediated inflammatory and
demyelinating disorder of the central nervous system, commonly preceded by an infection. It …

Baló's concentric sclerosis is often regarded as a rare variant of multiple sclerosis. Patients
with this disorder present with acute or subacute neurological deterioration, with MRI …

Tumefactive multiple sclerosis or tumefactive demyelinating lesion (TDL) is one of the rare
variants of multiple sclerosis (MS) posing a diagnostic challenge and a therapeutic enigma …

OBJECTIVE. Tumefactive demyelination mimics primary brain neoplasms on imaging, often
necessitating brain biopsy. This article reviews the literature for the clinical and radiologic …

Not all patients with pseudotumoral lesions require a brain biopsy but close follow-up of
biopsied and nonbiopsied lesions is indicated once a diagnosis is established. Testing for …

BACKGROUND: Accurate diagnosis of tumefactive demyelinating lesions is clinically
important to avoid unnecessary invasive biopsy or inappropriate treatment. PURPOSE: We …

Atypical lesions of a presumably idiopathic inflammatory demyelinating origin present quite
variably and may pose diagnostic problems. The subsequent clinical course is also …