Evolving knowledge regarding sex differences in coronary heart disease is emerging. Given
the lower burden of obstructive coronary artery disease (CAD) and preserved systolic …

KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

Coronary artery spasm (CAS), an intense vasoconstriction of coronary arteries that causes
total or subtotal vessel occlusion, plays an important role in myocardial ischemic syndromes …

Hypertension is often characterised by impaired vasodilation involving dysfunction of
multiple vasodilatory mechanisms. ω‐3 polyunsaturated fatty acids (PUFAs) …

ATP-sensitive potassium (KATP) channels are present in the surface and internal
membranes of cardiac, skeletal, and smooth muscle cells and provide a unique feedback …

ATP sensitive potassium channels (KATP) are so named because they open as cellular ATP
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …

ATP-sensitive potassium (KATP) channels were first discovered in the heart 30 years ago.
Reconstitution of KATP channel activity by coexpression of members of the pore-forming …

The control of force production in vascular smooth muscle is critical to the normal regulation
of blood flow and pressure, and altered regulation is common to diseases such as …

Globally, migraine is a leading cause of disability with a huge impact on both the work and
private life of affected persons. To overcome the societal migraine burden, better treatment …

Vasospastic angina (VSA) is an under-appreciated cause of chest pain. It is characterised by
transient vasoconstriction of the coronary arteries and plays a significant role in the …