The gut-brain axis and cognitive control: A role for the vagus nerve

L Décarie-Spain, AMR Hayes, LT Lauer… - Seminars in Cell & …, 2024 - Elsevier
Survival requires the integration of external information and interoceptive cues to effectively
guide advantageous behaviors, particularly foraging and other behaviors that promote …

Communal nesting differentially attenuates the impact of pre-weaning social isolation on behavior in male and female rats during adolescence and adulthood

J Bratzu, M Ciscato, A Pisanu, G Talani… - Frontiers in Behavioral …, 2023 - frontiersin.org
Introduction Early social isolation (ESI) disrupts neurodevelopmental processes, potentially
leading to long-lasting emotional and cognitive changes in adulthood. Communal nesting …

[HTML][HTML] Maternal separation as early-life stress: mechanisms of neuropsychiatric disorders and inspiration for neonatal care

Y Zhang, S Wang, M Hei - Brain Research Bulletin, 2024 - Elsevier
The establishment of positive early parent–infant relationships provide essential
nourishment and social stimulation for newborns. During the early stages of postnatal brain …

Long-term environmental enrichment overcomes depression, learning, and memory impairment in elderly CD-1 mice with maternal sleep deprivation exposure

YM Zhang, RM Wei, XY Li, YZ Feng… - Frontiers in Aging …, 2023 - frontiersin.org
Early-life stress disrupts central nervous system development and increases the risk of
neuropsychiatric disorder in offspring based on rodent studies. Maternal sleep deprivation …

Neonatal maternal separation induces sexual dimorphism in brain development: The influence on amino acid levels and cognitive disorders

JH Kotlinska, P Grochecki, A Michalak, A Pankowska… - Biomolecules, 2023 - mdpi.com
Repeated maternal separation (MS) is a useful experimental model in rodents for studying
the long-term influence of early-life stress on brain neurophysiology. In our work, we …

An enriched environment improves maternal sleep deprivation‐induced cognitive deficits and synaptic plasticity via hippocampal histone acetylation

YM Zhang, RM Wei, MZ Ni, QT Wu, Y Li… - Brain and …, 2023 - Wiley Online Library
Introduction Growing evidence clearly demonstrates that maternal rodents exposure to sleep
deprivation (SD) during late pregnancy impairs learning and memory in their offspring …

Dorsal CA1 Nectin3 reduction mediates early-life stress-induced object recognition memory deficits in adolescent female mice

YN Ma, CC Zhang, YX Sun, X Liu, XX Li, H Wang… - Neuroscience …, 2024 - Springer
Early-life stress (ES) leads to cognitive dysfunction in female adolescents, but the underlying
neural mechanisms remain elusive. Recent evidence suggests that the cell adhesion …

[HTML][HTML] Sex-specific changes in voluntary alcohol consumption and nucleus accumbens synaptic plasticity in C57BL/6J mice exposed to neonatal maternal …

G Talani, F Biggio, MC Mostallino, E Batzu, G Biggio… - …, 2025 - Elsevier
The long-term influence of early-life stress on brain neurophysiology has been extensively
investigated using different animal models. Among these, repeated maternal separation …

Activation of GPR55 Ameliorates Maternal Separation-Induced Learning and Memory Deficits by Augmenting 5-HT Synthesis in the Dorsal Raphe Nucleus of Juvenile …

T Sun, YY Du, YQ Zhang, QQ Tian, X Li, JY Yu… - ACS …, 2024 - ACS Publications
Maternal separation (MS) represents a profound early life stressor with enduring impacts on
neuronal development and adult cognitive function in both humans and rodents. MS is …

[HTML][HTML] Lateral habenula IL-10 controls GABAA receptor trafficking and modulates depression susceptibility after maternal separation

R Ding, Y Tang, G Cao, Y Mai, Y Fu, Z Ren, W Li… - Brain, Behavior, and …, 2024 - Elsevier
Maternal separation (MS), a form of early life adversity, increases the risk of psychiatric
disorders in adulthood by intricately linking cytokines and mood-regulating brain circuits …