Background Alcohol acts as an addictive substance that may lead to alcohol use disorder. In
humans, magnetic resonance imaging showed diverse structural and functional brain …

Female and male glial fibrillary acidic protein-thymidine kinase (GFAP-TK) transgenic rats
were made ethanol dependent via a six-week chronic intermittent ethanol vapor (CIE) and …

Previous studies demonstrate that ethanol dependence induced by repeating cycles of
chronic intermittent ethanol vapor exposure (CIE) followed by protracted abstinence …

Purpose Chronic ethanol exposure causes neurotoxicity and long-term learning and
memory impairment along with hippocampal and frontal cortical dysfunction. Flavonoids …

Angiogenesis or proliferation of endothelial cells plays a role in brain microenvironment
homeostasis. Previously we have shown enhanced expression of markers of angiogenesis …

Brain-imaging studies show that the development and maintenance of alcohol use disorder
(AUD) is determined by a complex interaction of different neurotransmitter systems and …

Introduction Alcohol dependence is characterized by a gradual reduction in cognitive control
and inflexibility to contingency changes. The neuroadaptations underlying this aberrant …

Alcohol consumption is associated with structural alterations in the brain parenchyma.
Understanding the longitudinal brain transformations that occur from an alcohol naïve state …

Alcohol use disorder (AUD) is highly prevalent in the United States with very few FDA
approved treatments that do not completely reduce relapse to alcohol seeking. This is due to …