EMT and tumor metastasis
S Heerboth, G Housman, M Leary, M Longacre… - Clinical and translational …, 2015 - Springer
EMT and MET comprise the processes by which cells transit between epithelial and
mesenchymal states, and they play integral roles in both normal development and cancer …
mesenchymal states, and they play integral roles in both normal development and cancer …
The oncogene ERG: a key factor in prostate cancer
P Adamo, MR Ladomery - Oncogene, 2016 - nature.com
ETS-related gene (ERG) is a member of the E-26 transformation-specific (ETS) family of
transcription factors with roles in development that include vasculogenesis, angiogenesis …
transcription factors with roles in development that include vasculogenesis, angiogenesis …
Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis
Tumor–stromal interaction is a dynamic process that promotes tumor growth and metastasis
via cell–cell interaction and extracellular vesicles. Recent studies demonstrate that stromal …
via cell–cell interaction and extracellular vesicles. Recent studies demonstrate that stromal …
Integrin-linked kinase (ILK): the known vs. the unknown and perspectives
A Górska, AJ Mazur - Cellular and Molecular Life Sciences, 2022 - Springer
Integrin-linked kinase (ILK) is a multifunctional molecular actor in cell–matrix interactions,
cell adhesion, and anchorage-dependent cell growth. It combines functions of a signal …
cell adhesion, and anchorage-dependent cell growth. It combines functions of a signal …
miR-409-3p/-5p promotes tumorigenesis, epithelial-to-mesenchymal transition, and bone metastasis of human prostate cancer
S Josson, M Gururajan, P Hu, C Shao, GCY Chu… - Clinical cancer …, 2014 - AACR
Abstract Purpose: miR-409-3p/-5p is a miRNA expressed by embryonic stem cells, and its
role in cancer biology and metastasis is unknown. Our pilot studies demonstrated elevated …
role in cancer biology and metastasis is unknown. Our pilot studies demonstrated elevated …
The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of …
E Khosh Kish, M Choudhry, Y Gamallat… - International journal of …, 2022 - mdpi.com
The ETS-related gene (ERG) is proto-oncogene that is classified as a member of the ETS
transcription factor family, which has been found to be consistently overexpressed in about …
transcription factor family, which has been found to be consistently overexpressed in about …
Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular …
MC Haffner, C Weier, MM Xu, A Vaghasia… - The Journal of …, 2016 - Wiley Online Library
Prostate cancer often manifests as morphologically distinct tumour foci and is frequently
found adjacent to presumed precursor lesions such as high‐grade prostatic intraepithelial …
found adjacent to presumed precursor lesions such as high‐grade prostatic intraepithelial …
ETS transcription factors as emerging drug targets in cancer
The ETS family of proteins consists of 28 transcription factors, many of which have been
implicated in development and progression of a variety of cancers. While one family …
implicated in development and progression of a variety of cancers. While one family …
ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer
Chromosomal translocations juxtaposing the androgen-responsive TMPRSS2 promoter with
the ETS-family transcription factor ERG result in aberrant ERG upregulation in approximately …
the ETS-family transcription factor ERG result in aberrant ERG upregulation in approximately …
[HTML][HTML] Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
P Ruzanov, V Evdokimova, MC Pachva… - The Journal of …, 2024 - Am Soc Clin Investig
JCI - Oncogenic ETS fusions promote DNA damage and proinflammatory responses via
pericentromeric RNAs in extracellular vesicles Go to JCI Insight About Editors Consulting Editors …
pericentromeric RNAs in extracellular vesicles Go to JCI Insight About Editors Consulting Editors …