Mammalian cells take up extracellular material by a variety of different mechanisms that are
collectively termed endocytosis. Endocytic mechanisms serve many important cellular …

Hepatocytes, like other epithelia, are situated at the interface between the organism's
exterior and the underlying internal milieu and organize the vectorial exchange of …

We show that a protein with a glycosylphosphatidyl inositol (GPI) anchor can be recovered
from lysates of epithelial cells in a low density, detergent-insoluble form. Under these …

Das macht das Buch aus: Der „Silbernagel “, wie viele dieses Buch nennen, zeichnet sich
durch die grobe Unterteilung in die zahlreichen klar strukturierten Kapitel aus, die häufig …

To automate examination of massive amounts of sequence data for biological function, it is
important to computerize interpretation based on empirical knowledge of sequence-function …

The polarity of neurons, which is integral to their function, is a result of the segregated
distribution of molecules and organelles. The polarized distribution of cytoskeletal proteins …

The crumbs protein of Drosophila is an integral membrane protein, with 30 EGF-like and 4
lamlnin AG domain-like repeats in its extracellular segment, which is expressed on the …

Membrane lipids were once thought to be homogenously distributed in the 2D surface of a
membrane, but the lipid raft theory suggests that cholesterol and sphingolipids partition …

Experiments using mammalian epithelial cell lines have elucidated biosynthetic and
recycling pathways for apical and basolateral plasma-membrane proteins, and have …

The trans-Golgi network (TGN) is the major sorting station in the secretory pathway of all
eukaryotic cells. How the TGN sorts proteins and lipids to generate the enrichment of …