New antifungal agents and new formulations against dermatophytes

AK Gupta, KA Foley, SG Versteeg - Mycopathologia, 2017 - Springer
A variety of oral and topical antifungal agents are available for the treatment of superficial
fungal infections caused by dermatophytes. This review builds on the antifungal therapy …

[HTML][HTML] Microsponges for dermatological applications: Perspectives and challenges

S Mahant, S Kumar, S Nanda, R Rao - Asian journal of pharmaceutical …, 2020 - Elsevier
Dermatological disorders have a huge psychosocial impact, causing significant impairment
of patient's life. Topical therapy plays a pivotal role in management of such disorders …

Improved vaginal retention and enhanced antifungal activity of miconazole microsponges gel: Formulation development and in vivo therapeutic efficacy in rats

S Salah, GEA Awad, AIA Makhlouf - European Journal of Pharmaceutical …, 2018 - Elsevier
Traditional azole antifungal formulations suffer from poor retention in the vaginal cavity,
irritation and burning of the vaginal area. In the present work, we aim at the development of …

Sertaconazole-PLGA nanoparticles for management of ocular keratitis

NE Eleraky, MA Attia, MA Safwat - Journal of Drug Delivery Science and …, 2024 - Elsevier
Ocular fungal infections can pose severe health conditions that may develop into vision
impairment and blindness. Sertaconazole (STZ) is a widely used antifungal; however, its low …

Sponge particulates for biomedical applications: Biofunctionalization, multi-drug shielding, and theranostic applications

H Zhang, Y Jin, C Chi, G Han, W Jiang, Z Wang… - Biomaterials, 2021 - Elsevier
Sponge particulates have attracted enormous attention in biomedical applications for
superior properties, including large porosity, elastic deformation, capillary action, and three …

Eudragit RS100 based microsponges for dermal delivery of clobetasol propionate in psoriasis management

N Devi, S Kumar, M Prasad, R Rao - Journal of drug delivery science and …, 2020 - Elsevier
Clobetasol propionate (CP), a super potent dihalogenated topical corticosteroid for
psoriasis, displays common side effects like allergic contact dermatitis, steroid acne, skin …

A review about the drug delivery from microsponges

MV Junqueira, ML Bruschi - AAPS PharmSciTech, 2018 - Springer
Microparticulate drug delivery systems have shown a great interest in the pharmaceutical
area. They allow the increase of drug therapeutic efficacy and the reduction of side effects. In …

Expedition of Eudragit® polymers in the development of novel drug delivery systems

SK Jain, AK Jain, K Rajpoot - Current drug delivery, 2020 - ingentaconnect.com
Eudragit® polymer has been widely used in film-coating for enhancing the quality of
products over other materials (eg, shellac or sugar). Eudragit® polymers are obtained …

[HTML][HTML] Development of clindamycin loaded oral microsponges (Clindasponges) for antimicrobial enhancement: In vitro characterization and simulated in vivo studies

RMF Sammour, G Khan, S Sameer, S Khan… - Biological and …, 2023 - jstage.jst.go.jp
Clindamycin phosphate (CLP) is a broad-spectrum antibiotic that is used widely for different
types of infections. It has a short half-life and hence it should be taken every six hours to …

Sulpiride gastro-retentive floating microsponges; analytical study, in vitro optimization and in vivo characterization

MA Younis, MR El-Zahry, MA Tallat… - Journal of drug …, 2020 - Taylor & Francis
Abstract Sulpiride (SUL), anti-dopaminergic drug, has a specific site for absorption located in
the upper portion of the gastrointestinal tract hence, its oral delivery represents a challenge …