Bioorthogonally assisted phototherapy: recent advances and prospects

E Kozma, M Bojtár, P Kele - Angewandte Chemie, 2023 - Wiley Online Library
Photoresponsive materials offer excellent spatiotemporal control over biological processes
and the emerging phototherapeutic methods are expected to have significant effects on …

Strategic Design of Luminescent Rhenium (I), Ruthenium (II), and Iridium (III) Complexes as Activity‐Based Probes for Bioimaging and Biosensing

LCC Lee, KKW Lo - Chemistry–An Asian Journal, 2022 - Wiley Online Library
The rapid development of responsive fluorescent probes has advanced optical imaging for
biological research and biomedical applications. Among different sensing strategies, activity …

Reduction of Platinum (IV) Prodrug Hemoglobin Nanoparticles with Deeply Penetrating Ultrasound Radiation for Tumor‐Targeted Therapeutically Enhanced …

G Liang, T Sadhukhan, S Banerjee… - Angewandte Chemie …, 2023 - Wiley Online Library
The development of PtIV prodrugs that are reduced into the therapeutically active PtII
species within the tumor microenvironment has received much research interest. In order to …

Design of near-infrared-triggered metallo-photosensitizers via a self-assembly-induced vibronic decoupling strategy

J Zhao, Y Gao, R Huang, C Chi, Y Sun… - Journal of the …, 2023 - ACS Publications
Development of highly efficient near-infrared (NIR)-excited photosensitizers is hampered by
the fast nonradiative vibrational relaxation process regulated by the energy gap law. Here …

Engineered bacteria labeled with iridium (III) photosensitizers for enhanced photodynamic immunotherapy of solid tumors

W Lin, Y Liu, J Wang, Z Zhao, K Lu, H Meng… - Angewandte …, 2023 - Wiley Online Library
Despite metal‐based photosensitizers showing great potential in photodynamic therapy for
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …

Exploring Structure–Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir (III)-COUPY Conjugates

A Rovira, E Ortega-Forte, C Hally… - Journal of Medicinal …, 2023 - ACS Publications
Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-
resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with …

Isomer engineering of lepidine-based iridophosphors for far-red hypoxia imaging and photodynamic therapy

P Tao, Z Lv, XK Zheng, H Jiang, S Liu, H Wang… - Inorganic …, 2022 - ACS Publications
The development of highly efficient cyclometalated phosphorescent iridium (III) complexes is
greatly promoted by their rational molecular design. Manipulating the excited states of …

More-is-better strategy for constructing homoligand polypyridyl ruthenium complexes as photosensitizers for infrared two-photon photodynamic therapy

SJ Tang, MF Wang, R Yang, M Liu, QF Li… - Inorganic …, 2023 - ACS Publications
Photodynamic therapy (PDT) uses a combination of photosensitizers (PSs), light sources,
and reactive oxygen species (ROS) to damage only the desired target and keep normal …

Biomedical applications of multinuclear Pt (II)/Ru (II)/Ir (III) metallo-supramolecular assemblies for intensive cancer therapy

X Li, X Zhao, W Wang, Z Shi, Y Zhang, Q Tian… - Coordination Chemistry …, 2023 - Elsevier
The development of highly efficient and minimally toxic agents with targeting abilities toward
tumor tissues is an ongoing area of research in the fight against cancer. Different from the …

Enhanced Deep-Red Phosphorescence in Cyclometalated Iridium Complexes with Quinoline-Based Ancillary Ligands

S Yoon, TG Gray, TS Teets - Inorganic Chemistry, 2023 - ACS Publications
Compounds with good photoluminescence quantum yields (ΦPL) in the deep-red to near-
infrared parts of the spectrum are desired for a variety of applications in optoelectronics …