[HTML][HTML] The development of collagen based composite scaffolds for bone regeneration

D Zhang, X Wu, J Chen, K Lin - Bioactive materials, 2018 - Elsevier
Bone is consisted of bone matrix, cells and bioactive factors, and bone matrix is the
combination of inorganic minerals and organic polymers. Type I collagen fibril made of five …

The role of phosphatases in the initiation of skeletal mineralization

JL Millán - Calcified tissue international, 2013 - Springer
Endochondral ossification is a carefully orchestrated process mediated by promoters and
inhibitors of mineralization. Phosphatases are implicated, but their identities and functions …

Role of matrix vesicles in biomineralization

EE Golub - Biochimica et Biophysica Acta (BBA)-General Subjects, 2009 - Elsevier
BACKGROUND: Matrix vesicles have been implicated in the mineralization of calcified
cartilage, bone and dentin for more than 40 years. During this period, their exact role, if any …

Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies

YC Chai, A Carlier, J Bolander, SJ Roberts, L Geris… - Acta biomaterialia, 2012 - Elsevier
Calcium phosphate (CaP) has traditionally been used for the repair of bone defects because
of its strong resemblance to the inorganic phase of bone matrix. Nowadays, a variety of …

[HTML][HTML] Characterisation of matrix vesicles in skeletal and soft tissue mineralisation

L Cui, DA Houston, C Farquharson, VE MacRae - Bone, 2016 - Elsevier
The importance of matrix vesicles (MVs) has been repeatedly highlighted in the formation of
cartilage, bone, and dentin since their discovery in 1967. These nano-vesicular structures …

Functions of vitamin D in bone

D Goltzman - Histochemistry and cell biology, 2018 - Springer
Vitamin D, synthesized in the skin or absorbed from the diet, undergoes multi-step enzymatic
conversion to its active form, 1, 25-dihydroxy vitamin D [1, 25 (OH) 2 D], followed by …

Extracellular vesicles as mediators of cardiovascular calcification

A Bakhshian Nik, JD Hutcheson… - Frontiers in cardiovascular …, 2017 - frontiersin.org
Involvement of cell-derived extracellular particles, coined as matrix vesicles (MVs), in
biological bone formation was introduced by Bonucci and Anderson in mid-1960s. In 1983 …

Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of …

MC Yadav, AMS Simão, S Narisawa… - Journal of Bone and …, 2011 - academic.oup.com
Endochondral ossification is a carefully orchestrated process mediated by promoters and
inhibitors of mineralization. Phosphatases are implicated, but their identities and functions …

Role of metabolism in bone development and homeostasis

A Suzuki, M Minamide, C Iwaya, K Ogata… - International journal of …, 2020 - mdpi.com
Carbohydrates, fats, and proteins are the underlying energy sources for animals and are
catabolized through specific biochemical cascades involving numerous enzymes. The …

Ultrastructure and biological function of matrix vesicles in bone mineralization

T Hasegawa - Histochemistry and Cell Biology, 2018 - Springer
Bone mineralization is initiated by matrix vesicles, small extracellular vesicles secreted by
osteoblasts, inducing the nucleation and subsequent growth of calcium phosphate crystals …