Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …

Severe traumatic brain injury (TBI) is currently managed in the intensive care unit with a
combined medical–surgical approach. Treatment aims to prevent additional brain damage …

A substantial minority of patients who survive an acquired brain injury develop a state of
sympathetic hyperactivity that can persist for weeks or months, consisting of periodic …

A syndrome of paroxysmal, episodic sympathetic hyperactivity after acquired brain injury has
been recognized for almost 60 years. This project sought to simplify the confused …

A mild traumatic brain injury (mTBI) is a complex pathophysiologic process that has a
systemic effect on the body aside from solely an impairment in cognitive function …

As head injuries and their sequelae have become an increasingly salient matter of public
health, experts in the field have made great progress elucidating the biological processes …

Severe excessive autonomic overactivity occurs in a subgroup of people surviving acquired
brain injury, the majority of whom show paroxysmal sympathetic and motor overactivity …

The gut microbiome and its role in health and disease have recently been major focus areas
of research. In this review, we summarize the different ways in which the gut microbiome …

Paroxysmal sympathetic hyperactivity (PSH) has predominantly been described after
traumatic brain injury (TBI), which is associated with hyperthermia, hypertension …

Severe traumatic brain injury (sTBI) is a major contributor to long-term disability and a
leading cause of death worldwide. Medical management of the sTBI patient, beginning with …