[HTML][HTML] The pharmacological potential of rutin

A Ganeshpurkar, AK Saluja - Saudi pharmaceutical journal, 2017 - Elsevier
The contemporary scientific community has presently recognized flavonoids to be a unique
class of therapeutic molecules due to their diverse therapeutic properties. Of these, rutin …

Preclinical evidence for the pharmacological actions of naringin: a review

S Bharti, N Rani, B Krishnamurthy, DS Arya - Planta medica, 2014 - thieme-connect.com
Naringin, chemically 4′, 5, 7-trihydroxyflavanone-7-rhamnoglucoside, is a major flavanone
glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. It has been …

Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells

M Kedhari Sundaram, R Raina, N Afroze… - Bioscience …, 2019 - portlandpress.com
Cancer cells have the unique ability to overcome natural defense mechanisms, undergo
unchecked proliferation and evade apoptosis. While chemotherapeutic drugs address this …

Protective effects of the hydroalcoholic extract of Fumaria parviflora on testicular injury induced by torsion/detorsion in adult rats

M Shokoohi, H Shoorei, M Soltani… - Andrologia, 2018 - Wiley Online Library
This study was designed to determine the effects of daily oral administration (250 mg/kg) of
the hydroalcoholic extract of Fumaria parviflora (FP) for 14 days on the sperm parameters …

Naringin attenuates alcoholic liver injury by reducing lipid accumulation and oxidative stress

C Zhou, Y Lai, P Huang, L Xie, H Lin, Z Zhou, C Mo… - Life sciences, 2019 - Elsevier
Aims Alcoholic liver disease (ALD) is a leading health risk worldwide, which can induce
hepatic steatosis, progressive fibrosis, cirrhosis and even carcinoma. As a potential …

Therapeutic potential of rutin in male infertility: a mini review

DE Rotimi, TC Elebiyo, OA Ojo - Journal of Integrative Medicine, 2023 - Elsevier
Male infertility has become a problem worldwide, and recent research has emphasized the
development of more effective therapy options. Among natural compounds, rutin has been …

Chlorogenic acid, rutin, and quercetin from Lysimachia christinae alleviate triptolide-induced multi-organ injury in vivo by modulating immunity and AKT/mTOR signal …

X Wu, J Wang, B Li, M Gong, C Cao, L Song… - Toxicology and Applied …, 2023 - Elsevier
Drug-induced organ injury is one of the key factors causing organ failure and death in the
global public. Triptolide (TP) is the main immunosuppressive component of Tripterygium …

Protective effect of rutin against brain injury induced by acrylamide or gamma radiation: Role of PI3K/AKT/GSK-3β/NRF-2 signalling pathway

NM Thabet, EM Moustafa - Archives of physiology and …, 2018 - Taylor & Francis
This study was designed to evaluate the effect of rutin on PI3K/AKT-signalling in case of
acrylamide or γ-radiation-induced neurotoxicity. To induce brain damage, animals were …

The effect of rutin on ovarian ischemia-reperfusion injury in a rat model

C Nayki, U Nayki, F Keskin Cimen… - Gynecological …, 2018 - Taylor & Francis
The effect of rutin on ovarian ischemia-reperfusion (I/R) injury was investigated in this
experimental study. Eighteen Wistar albino female rats were divided into three groups as …

Rutin ameliorates methotrexate induced hepatic injury in rats

E Erdogan, Y Ilgaz, PN Gurgor, Y Oztas… - Acta cirurgica …, 2015 - SciELO Brasil
PURPOSE: To investigate the possible protective effect of rutin on methotrexate induced
hepatotoxicity in rats. METHODS: Twenty-two rats were divided into three experimental …