Reservoirs and transmission routes of leprosy; A systematic review

T Ploemacher, WR Faber, H Menke… - PLoS neglected …, 2020 - journals.plos.org
Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the
more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy …

Mycobacterium lepromatosis as a Second Agent of Hansen's Disease

P Deps, SM Collin - Frontiers in Microbiology, 2021 - frontiersin.org
Mycobacterium lepromatosis was identified as a new species and second causal agent of
Hansen's disease (HD, or leprosy) in 2008, 150years after the disease was first attributed to …

Red squirrels in the British Isles are infected with leprosy bacilli

C Avanzi, J Del-Pozo, A Benjak, K Stevenson… - Science, 2016 - science.org
Leprosy, caused by infection with Mycobacterium leprae or the recently discovered
Mycobacterium lepromatosis, was once endemic in humans in the British Isles. Red …

[HTML][HTML] Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe

VJ Schuenemann, C Avanzi, B Krause-Kyora… - PLoS …, 2018 - journals.plos.org
Studying ancient DNA allows us to retrace the evolutionary history of human pathogens,
such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the …

Pathogenicity and virulence of Mycobacterium leprae

M Sugawara-Mikami, K Tanigawa, A Kawashima… - Virulence, 2022 - Taylor & Francis
Leprosy is caused by Mycobacterium leprae (M. leprae) and M. lepromatosis, an obligate
intracellular organism, and over 200,000 new cases occur every year. M. leprae parasitizes …

Mycobacterium leprae transmission characteristics during the declining stages of leprosy incidence: A systematic review

T Hambridge, SL Nanjan Chandran… - PLoS neglected …, 2021 - journals.plos.org
Background Leprosy is an infectious disease caused by Mycobacterium leprae. As
incidence begins to decline, the characteristics of new cases shifts away from those …

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos

MB da Silva, JM Portela, W Li, M Jackson… - PLoS neglected …, 2018 - journals.plos.org
Mycobacterium leprae (M. leprae) is a human pathogen and the causative agent for leprosy,
a chronic disease characterized by lesions of the skin and peripheral nerve damage …

Molecular Evidence for the Aerial Route of Infection of Mycobacterium leprae and the Role of Asymptomatic Carriers in the Persistence of Leprosy

S Araujo, LO Freitas, LR Goulart… - Clinical Infectious …, 2016 - academic.oup.com
Background Leprosy persists as a public health problem. The chain of transmission and
mechanism of infection are not completely understood. In the current study, we investigated …

Multidrug therapy for leprosy: a game changer on the path to elimination

CS Smith, A Aerts, P Saunderson… - The Lancet Infectious …, 2017 - thelancet.com
Leprosy is present in more than 100 countries, where it remains a major cause of peripheral
neuropathy and disability. Attempts to eliminate the disease have faced various obstacles …

2000-year-old pathogen genomes reconstructed from metagenomic analysis of Egyptian mummified individuals

J Neukamm, S Pfrengle, M Molak, A Seitz, M Francken… - BMC biology, 2020 - Springer
Background Recent advances in sequencing have facilitated large-scale analyses of the
metagenomic composition of different samples, including the environmental microbiome of …