The human major histocompatibility complex is a family of genes that encodes HLAs, which
have a crucial role in defence against foreign pathogens and immune surveillance of …

Considerable research has established an association between human leukocyte antigen
antibodies and chronic rejection. Two new major developments now provide evidence that …

We conducted a nested case–control study from a cohort of adult kidney transplant
recipients to assess the risk of transplant glomerulopathy (TG) as a function of donor and …

This report describes the design of the eplet version of HLAMatchmaker to determine class II
compatibility at the structural level. This matching algorithm is based on the hypothesis …

Since its inception in the early 1960s, the serologically based complement‐dependent
cytotoxicity (CDC) assay has been the cornerstone technique for the detection of human …

In an effort to prepare non-autologous bone graft or biomaterial that would possess
characteristics comparable to autologous bone, many different allogenic bone derivatives …

Kidney transplantation remains the treatment of choice for end‐stage renal failure. When the
immune system of the recipient recognizes the transplanted kidney as a foreign object, graft …

Background It is widely accepted that HLA donor-specific antibodies (DSA) are associated
with antibody-mediated rejection and graft loss. However, in many transplant programs …

Donor‐specific HLA alloantibodies may cause acute and chronic antibody‐mediated
rejection (AMR) and significantly compromise allograft survival. The clinical relevance of …

Living donor kidney transplantation in crossmatch‐positive patients is a challenge that
requires specific measures. Ten patients with positive crossmatch results (n= 9) or negative …