Clostridioides difficile infection (CDI) is a serious disease with a high recurrence rate. The
single and mixed biofilms formed by C. difficile in the gut contribute to the formation of …

Clostridioides difficile infections are an urgent medical problem. The newly discovered C.
difficile a denine m ethyltransferase A (CamA) is specified by all C. difficile genomes …

Highly persistent, drug-resistant and transmissible healthcare pathogens such as
Clostridioides difficile (C. difficile) and Candida auris (C. auris) are responsible for causing …

Spore-forming bacteria are a major concern for the food industry as they cause both
spoilage and food safety issues. Moreover, as they are more resistant than vegetative cells …

Epigenetically targeted therapeutic development, particularly for SAM-dependent
methylations of DNA, mRNA and histones has been proceeding rapidly for cancer …

Aim To evaluate in a laboratory setting the influence of several model system parameters on
the sodium hypochlorite (NaOCl) susceptibility of endodontic biofilms. Based on these …

The bacterial stringent response (SR) is a conserved transcriptional reprogramming
pathway mediated by the nucleotide signaling alarmones,(pp) pGpp. The SR has been …

Background Pre-wetted disinfectant wipes are increasingly being used in healthcare
facilities to help address the risk of healthcare associated infections (HAIs). However, HAIs …

Background Clostridioides difficile infections (CDI) and recurrence (rCDI) are major health
care burdens. Recurrence is likely caused by spores in the gastrointestinal tract that …

Abstract Objectives Patients with Clostridioides difficile infection (CDI) who receive treatment
at outpatient infusion centers (OICs) pose a risk for spore transmission. We investigated C …