Antibiotic resistance in Chlamydiae

KM Sandoz, DD Rockey - Future microbiology, 2010 - Taylor & Francis
There are few documented reports of antibiotic resistance in Chlamydia and no examples of
natural and stable antibiotic resistance in strains collected from humans. While there are …

[HTML][HTML] Chlamydial infection from outside to inside

A Gitsels, N Sanders, D Vanrompay - Frontiers in Microbiology, 2019 - frontiersin.org
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …

Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

SR Harris, IN Clarke, HMB Seth-Smith, AW Solomon… - Nature …, 2012 - nature.com
Chlamydia trachomatis is responsible for both trachoma and sexually transmitted infections,
causing substantial morbidity and economic cost globally. Despite this, our knowledge of its …

[HTML][HTML] Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny

LDW Luu, V Kasimov, S Phillips, GSA Myers… - Frontiers in cellular …, 2023 - frontiersin.org
The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals, including C. trachomatis and C. pneumoniae. Since 1998, when the …

Horizontal Transfer of Tetracycline Resistance among Chlamydia spp. In Vitro

RJ Suchland, KM Sandoz, BM Jeffrey… - Antimicrobial agents …, 2009 - Am Soc Microbiol
There are no examples of stable tetracycline resistance in clinical strains of Chlamydia
trachomatis. However, the swine pathogen Chlamydia suis is commonly tetracycline …

Generation of targeted Chlamydia trachomatis null mutants

L Kari, MM Goheen, LB Randall… - Proceedings of the …, 2011 - National Acad Sciences
Chlamydia trachomatis is an obligate intracellular bacterial pathogen that infects hundreds
of millions of individuals globally, causing blinding trachoma and sexually transmitted …

Whole-genome sequences of Chlamydia trachomatis directly from clinical samples without culture

HMB Seth-Smith, SR Harris, RJ Skilton… - Genome …, 2013 - genome.cshlp.org
The use of whole-genome sequencing as a tool for the study of infectious bacteria is of
growing clinical interest. Chlamydia trachomatis is responsible for sexually transmitted …

Genome Sequencing of Recent Clinical Chlamydia trachomatis Strains Identifies Loci Associated with Tissue Tropism and Regions of Apparent Recombination

BM Jeffrey, RJ Suchland, KL Quinn… - Infection and …, 2010 - Am Soc Microbiol
The human pathogen Chlamydia trachomatis exists as multiple serovariants that have
distinct organotropisms for different tissue sites. Culture and epidemiologic data have …

Polymorphisms in the Nine Polymorphic Membrane Proteins of Chlamydia trachomatis across All Serovars: Evidence for Serovar Da Recombination and Correlation …

JP Gomes, A Nunes, WJ Bruno, MJ Borrego… - Journal of …, 2006 - Am Soc Microbiol
Chlamydia trachomatis is an intracellular bacterium responsible for ocular, respiratory, and
sexually transmitted diseases. The genome contains a nine-member polymorphic …

Evolution of Chlamydia trachomatis diversity occurs by widespread interstrain recombination involving hotspots

JP Gomes, WJ Bruno, A Nunes, N Santos… - Genome …, 2007 - genome.cshlp.org
Chlamydia trachomatis is an obligate intracellular bacterium of major public health
significance, infecting over one-tenth of the world's population and causing blindness and …