Mechanisms of genotoxicity. A review of in vitro and in vivo studies with engineered nanoparticles

Z Magdolenova, A Collins, A Kumar, A Dhawan… - …, 2014 - Taylor & Francis
Engineered nanoparticles (NPs) are widely used in different technologies but their unique
properties might also cause adverse health effects. In reviewing recent in vitro and in vivo …

Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies

S Bonassi, R El-Zein, C Bolognesi, M Fenech - Mutagenesis, 2011 - academic.oup.com
Over a century ago, Theodor Boveri paved the way to mechanistic studies linking
chromosomal abnormalities to cancer pathogenesis. Since then, theoretical and empirical …

Review of evidence on health aspects of air pollution: REVIHAAP project: technical report

World Health Organization - 2021 - apps.who.int
This document presents answers to 24 questions relevant to reviewing European policies on
air pollution and to addressing health aspects of these policies. The answers were …

Space radiation biology for “Living in Space”

S Furukawa, A Nagamatsu, M Nenoi… - BioMed Research …, 2020 - Wiley Online Library
Space travel has advanced significantly over the last six decades with astronauts spending
up to 6 months at the International Space Station. Nonetheless, the living environment while …

DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death

S Bonassi, M Ceppi, P Møller, A Azqueta, M Milić… - Scientific Reports, 2021 - nature.com
The comet assay or single cell gel electrophoresis, is the most common method used to
measure strand breaks and a variety of other DNA lesions in human populations. To …

Non-targeted effects of ionising radiation—implications for low dose risk

M Kadhim, S Salomaa, E Wright, G Hildebrandt… - … Research/Reviews in …, 2013 - Elsevier
Non-DNA targeted effects of ionising radiation, which include genomic instability, and a
variety of bystander effects including abscopal effects and bystander mediated adaptive …

Biological effects of low-dose chest CT on chromosomal DNA

H Sakane, M Ishida, L Shi, W Fukumoto, C Sakai… - Radiology, 2020 - pubs.rsna.org
Background Although the National Lung Screening Trial reported a significant reduction in
lung cancer mortality when low-dose (LD) CT chest examinations are used for a diagnosis …

[HTML][HTML] Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

M Dusinska, J Tulinska, N El Yamani… - Food and Chemical …, 2017 - Elsevier
The unique properties of nanomaterials (NMs) are beneficial in numerous industrial and
medical applications. However, they could also induce unintended effects. Thus, a proper …

Genotoxicity testing: progress and prospects for the next decade

H Turkez, ME Arslan, O Ozdemir - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Genotoxicity and mutagenicity analyses have a significant role in the
identification of hazard effects of therapeutic drugs, cosmetics, agrochemicals, industrial …

Assessing cancer risks of low-dose radiation

L Mullenders, M Atkinson, H Paretzke… - Nature Reviews …, 2009 - nature.com
Ionizing radiation is considered a non-threshold carcinogen. However, quantifying the risk of
the more commonly encountered low and/or protracted radiation exposures remains …