Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms
The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …
pollutants and are known to exert severe adverse impacts on the nervous system even at …
Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis
W Liu, Y Xin, Q Li, Y Shang, Z Ping, J Min… - Environmental …, 2020 - Springer
Background Although prior studies showed a correlation between environmental
manganese (Mn) exposure and neurodevelopmental disorders in children, the results have …
manganese (Mn) exposure and neurodevelopmental disorders in children, the results have …
[HTML][HTML] A benchmark concentration analysis for manganese in drinking water and IQ deficits in children
Background Manganese is an essential nutrient, but in excess, can be a potent
neurotoxicant. We previously reported findings from two cross-sectional studies on children …
neurotoxicant. We previously reported findings from two cross-sectional studies on children …
Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity
CJ Mercadante, M Prajapati… - The Journal of …, 2019 - Am Soc Clin Investig
Manganese (Mn), an essential metal and nutrient, is toxic in excess. Toxicity classically
results from inhalational exposures in individuals who work in industrial settings. The first …
results from inhalational exposures in individuals who work in industrial settings. The first …
Genetics and epigenetics of manganese toxicity
S Lindner, R Lucchini, K Broberg - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review At elevated levels, the essential element manganese (Mn) is
neurotoxic and increasing evidence indicates that environmental Mn exposure early in life …
neurotoxic and increasing evidence indicates that environmental Mn exposure early in life …
An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies
MZ Bocato, JP Bianchi Ximenez… - Journal of Toxicology …, 2019 - Taylor & Francis
Human Biomonitoring (HB), the process for determining whether and to what extent
chemical substances penetrated our bodies, serves as a useful tool to quantify human …
chemical substances penetrated our bodies, serves as a useful tool to quantify human …
Effect of exposure to endocrine disrupting chemicals in obesity and neurodevelopment: The genetic and microbiota link
V Ramírez, P González-Palacios, MA Baca… - Science of The Total …, 2022 - Elsevier
Current evidence highlights the importance of the genetic component in obesity and
neurodevelopmental disorders (attention-deficit hyperactivity disorder (ADHD), autism …
neurodevelopmental disorders (attention-deficit hyperactivity disorder (ADHD), autism …
Role of excretion in manganese homeostasis and neurotoxicity: a historical perspective
The essential metal manganese (Mn) induces incurable neurotoxicity at elevated levels that
manifests as parkinsonism in adults and fine motor and executive function deficits in …
manifests as parkinsonism in adults and fine motor and executive function deficits in …
Sex-specific differences in cognitive abilities associated with childhood cadmium and manganese exposures in school-age children: a prospective cohort study
T Zhou, J Guo, J Zhang, H Xiao, X Qi, C Wu… - Biological trace element …, 2020 - Springer
To examine sex-specific associations of neonatal and childhood exposure to eight trace
elements with cognitive abilities of school-age children. The association between exposure …
elements with cognitive abilities of school-age children. The association between exposure …
[HTML][HTML] Manganese transporter genetics and sex modify the association between environmental manganese exposure and neurobehavioral outcomes in children
There is increasing evidence that environmental manganese (Mn) exposure early in life can
have negative effects on children's neurodevelopment and increase the risk of behavioral …
have negative effects on children's neurodevelopment and increase the risk of behavioral …