The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

The synaptic hypothesis of schizophrenia has been highly influential. However, new
approaches mean there has been a step-change in the evidence available, and some tenets …

Over the past several decades, significant advances have been made in our understanding
of the basic stages and mechanisms of mammalian brain development. Studies elucidating …

Schizophrenia is a disease of abnormal brain development. Considerable evidence now
indicates that environmental factors have a causative role in schizophrenia. Elevated …

Spanning functions from the simplest reflex arc to complex cognitive processes, neural
circuits have diverse functional roles. In the cerebral cortex, functional domains such as …

We report the dynamic anatomical sequence of human cortical gray matter development
between the age of 4–21 years using quantitative four-dimensional maps and time-lapse …

To successfully negotiate the developmental transition between youth and adulthood,
adolescents must maneuver this often stressful period while acquiring skills necessary for …

Vulnerable periods during the development of the nervous system are sensitive to
environmental insults because they are dependent on the temporal and regional emergence …

The term'social brain'refers to the network of brain regions that are involved in
understanding others. Behaviour that is related to social cognition changes dramatically …

The preschool years represent a time of expansive mental growth, with the initial expression
of many psychological abilities that will continue to be refined into young adulthood …