This review focuses on the type A cytochrome c oxidases (C c O), which are found in all
mitochondria and also in several aerobic bacteria. C c O catalyzes the respiratory reduction …

On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Cytochrome c oxidase (CcO), the terminal oxidase of cell respiration, reduces molecular
oxygen (O2) in a reaction that is coupled with proton pumping. Since the discovery of this …

In the final steps of energy conservation in aerobic organisms, free energy from electron
transfer through the respiratory chain is transduced into a proton electrochemical gradient …

▪ Abstract Cytochrome c oxidase, the terminal enzyme of the respiratory chains of
mitochondria and aerobic bacteria, catalyzes electron transfer from cytochrome c to …

▪ Abstract Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the
energy made available from electron transfer reactions to transport protons across the inner …

The crystal structures of cytochrome c oxidase from both bovine and Paracoccus
denitrificans reveal two putative proton input channels that connect the heme-copper center …

A series of metalloprotein complexes embedded in a mitochondrial or bacterial membrane
utilize electron transfer reactions to pump protons across the membrane and create an …

The reaction with dioxygen of solubilized fully-reduced wild-type and EQ (I-286)(exchange
of glutamate 286 of subunit I for glutamine) mutant cytochrome c oxidase from Rhodobacter …

During each turnover of cytochrome oxidase (dioxygen reduced to water), eight protons are
taken up from the inside of the membrane, four protons being used for chemistry (water …