Understanding the birth of rupture-prone and irreparable micronuclei
Micronuclei are extra-nuclear bodies mainly derived from ana-telophase lagging
chromosomes/chromatins (LCs) that are not incorporated into primary nuclei at mitotic exit …
chromosomes/chromatins (LCs) that are not incorporated into primary nuclei at mitotic exit …
[HTML][HTML] Moonlighting in mitosis: analysis of the mitotic functions of transcription and splicing factors
Moonlighting proteins can perform one or more additional functions besides their primary
role. It has been posited that a protein can acquire a moonlighting function through a …
role. It has been posited that a protein can acquire a moonlighting function through a …
Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer
W Su, S Feng, X Chen, X Yang, R Mao, C Guo, Z Wang… - Cancer research, 2018 - AACR
The long noncoding RNA (lncRNA) MIR22HG has previously been identified as a prognostic
marker in hepatocellular carcinoma. Here, we performed a comprehensive analysis of …
marker in hepatocellular carcinoma. Here, we performed a comprehensive analysis of …
Nuclear Morphological abnormalities in Cancer: a search for unifying mechanisms
Irregularities in nuclear shape and/or alterations to nuclear size are a hallmark of
malignancy in a broad range of cancer types. Though these abnormalities are commonly …
malignancy in a broad range of cancer types. Though these abnormalities are commonly …
[HTML][HTML] LINC00857 interacting with YBX1 to regulate apoptosis and autophagy via MET and phosphor-AMPKa signaling
W Su, L Wang, H Zhao, S Hu, Y Zhou, C Guo… - … Therapy-Nucleic Acids, 2020 - cell.com
Long noncoding RNA (lncRNA) LINC00857 has been reported to be upregulated in lung
cancer and related to poor patient survival. It can regulate cell proliferation and tumor growth …
cancer and related to poor patient survival. It can regulate cell proliferation and tumor growth …
Intracellular colocalization of influenza viral RNA and Rab11A is dependent upon microtubule filaments
E Nturibi, AR Bhagwat, S Coburn, MM Myerburg… - Journal of …, 2017 - Am Soc Microbiol
Influenza A virus (IAV) consists of eight viral RNA (vRNA) segments that are replicated in the
host cell nucleus and transported to the plasma membrane for packaging into progeny …
host cell nucleus and transported to the plasma membrane for packaging into progeny …
[HTML][HTML] Nuclear dynamics and chromatin structure: implications for pancreatic cancer
Changes in nuclear shape have been extensively associated with the dynamics and
functionality of cancer cells. In most normal cells, nuclei have a regular ellipsoid shape and …
functionality of cancer cells. In most normal cells, nuclei have a regular ellipsoid shape and …
[HTML][HTML] Influenza virus induces cholesterol-enriched endocytic recycling compartments for budozone formation via cell cycle-independent centrosome maturation
A Kawaguchi, M Hirohama, Y Harada, S Osari… - PLoS …, 2015 - journals.plos.org
Influenza virus particles are assembled at the plasma membrane in concert with
incorporation of the virus genome, but the details of its spatio-temporal regulation are not …
incorporation of the virus genome, but the details of its spatio-temporal regulation are not …
[HTML][HTML] Intramolecular interaction of NEP regulated by CRM1 ensures the unidirectional transport of M1 for the nuclear export of influenza viral ribonucleoprotein
M Hirohama, S Yamashita, MN Asaka, T Kuroki… - Frontiers in …, 2023 - frontiersin.org
Introduction The influenza virus genome consists of single-stranded RNAs and forms viral
ribonucleoprotein (RNP) complexes. After viral genome replication in the nucleus, the viral …
ribonucleoprotein (RNP) complexes. After viral genome replication in the nucleus, the viral …
[HTML][HTML] At the interface of three nucleic acids: The role of RNA-binding proteins and poly (ADP-ribose) in DNA repair
EE Alemasova, OI Lavrik - Acta Naturae (англоязычная версия), 2017 - cyberleninka.ru
RNA-binding proteins (RBPs) regulate RNA metabolism, from synthesis to decay. When
bound to RNA, RBPs act as guardians of the genome integrity at different levels, from DNA …
bound to RNA, RBPs act as guardians of the genome integrity at different levels, from DNA …