A Systematic Review on Novel Mycobacterium tuberculosis Antigens and Their Discriminatory Potential for the Diagnosis of Latent and Active Tuberculosis

NR Meier, M Jacobsen, THM Ottenhoff… - Frontiers in …, 2018 - frontiersin.org
Background: Current immunodiagnostic tests for tuberculosis (TB) are based on the
detection of an immune response toward mycobacterial antigens injected into the skin or …

Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives

S Wei, T Xu, Y Chen, K Zhou - Emerging Microbes & Infections, 2023 - Taylor & Francis
Klebsiella pneumoniae is a notorious nosocomial pathogen causing a wide range of
infections. The increasing trend of antimicrobial resistance obtained by the species …

Exploring the potential of exosomes as biomarkers in tuberculosis and other diseases

R Arya, BP Jit, V Kumar, JJ Kim - International Journal of Molecular …, 2024 - mdpi.com
Tuberculosis (TB) is a major cause of morbidity and mortality and remains an important
public health issue in developing countries worldwide. The existing methods and techniques …

Microarray-based selection of a serum biomarker panel that can discriminate between latent and active pulmonary TB

Z Li, J Hu, P Liu, D Cui, H Di, S Wu - Scientific Reports, 2021 - nature.com
Bacterial culture of M. tuberculosis (MTB), the causative agent of tuberculosis (TB), from
clinical specimens is the gold standard for laboratory diagnosis of TB, but is slow and culture …

Up‐regulation of inflammatory reactions by MPT32, a secreted protein of Mycobacterium tuberculosis in RAW264.7 macrophages

HD Kim, H Choi, F Abekura, J Park… - Journal of Cellular …, 2023 - Wiley Online Library
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and is still one of the
global health burdens. The occurrence of various cases and multidrug resistance confirm …

Immunomodulatory effect of mycobacterial outer membrane vesicles coated nanoparticles

E George, A Goswami, T Lodhiya, P Padwal, S Iyer… - Biomaterials …, 2022 - Elsevier
Tuberculosis (TB) is one of the most widely prevalent infectious diseases that cause
significant mortality. Bacillus Calmette-Guérin (BCG), the current TB vaccine used in clinics …

Tuberculosis patients display a high proportion of CD8+ T cells with a high cytotoxic potential

L Chávez‐Galán, J Illescas‐Eugenio… - Microbiology and …, 2019 - Wiley Online Library
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) and
remains a major cause of morbidity and mortality worldwide. In the host's immune response …

In Silico Identification of Novel Immunogenic Secreted Proteins of Mycoplasma bovis from Secretome Data and Experimental Verification

I Shirani, H Zhang, G Zhao, S Lu, MA Marawan… - Pathogens, 2020 - mdpi.com
Mycoplasma bovis is a major pathogen, responsible for bovine respiratory diseases
worldwide. The present lack of effective control measures leaves cattle owners at …

Exploring the role of secretory proteins in the human infectious diseases diagnosis and therapeutics

E Kalita, M Panda, A Rao, VK Prajapati - Advances in Protein Chemistry …, 2023 - Elsevier
Secretory proteins are playing important role during the host-pathogen interaction to
develop the infection or protection into the cell. Pathogens developing infectious disease to …

Computational identification and characterization of antigenic properties of Rv3899c of Mycobacterium tuberculosis and its interaction with human leukocyte antigen …

R Das, K Eniyan, U Bajpai - Immunogenetics, 2021 - Springer
A rise in drug-resistant tuberculosis (TB) cases demands continued efforts towards the
discovery and development of drugs and vaccines. Secretory proteins of Mycobacterium …