The placenta is a transient organ but essential for the survival of all mammalian species by
allowing for the exchanges of gasses, nutrients, and waste between maternal and fetal …

Since its identification, 75 years ago, the monoamine serotonin (5-HT) has attracted
considerable attention toward its role as a neurotransmitter in the central nervous system …

Fetuses are exposed to many environmental perturbations that can influence their
development. These factors can be easily identifiable such as drugs, chronic diseases or …

Obesity and gestational diabetes mellitus (GDM) are becoming more common among
pregnant women worldwide and are individually associated with a number of placenta …

Abstract Serotonin [5-hydroxytryptamine (5-HT)] is essential to intrauterine development, but
its source is debated. We used immunocytochemistry to gauge 5-HT, its biosynthetic enzyme …

The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger
widely distributed in the brain and various other organs. Its homeostasis is maintained by the …

Aim Serotonin is crucial for proper foetal development, and the placenta has been described
as a 'donor'of serotonin for the embryo/foetus. However, in later stages of gestation the …

Human endothelial dysfunction is a common feature in many diseases of pregnancy, such
as gestational diabetes (GD). Metabolic changes include abnormal synthesis of nitric oxide …

There is a growing need to understand the potential neurotoxicity of organophosphate flame
retardants (OPFRs) and plasticizers because use and, consequently, human exposure, is …

We have reviewed the scientific literature related to four diseases in which to serotonin (5-
HT) is involved in the etiology, herein named 5-HT-linked diseases, and whose prevalence …