Macrophages are critically involved in wound healing, from dampening inflammation to
clearing cell debris and coordinating tissue repair. Within the wound, the complexity of …

Macrophages are innate immune cells with essential roles in host defense, inflammation,
immune regulation and repair. During infection with multicellular helminth parasites …

Macrophages, the major population of tissue‐resident mononuclear phagocytes, contribute
significantly to the immune response during helminth infection. Alternatively activated …

Ym1 and RELMα are established effector molecules closely synonymous with Th2-type
inflammation and associated pathology. Here, we show that whilst largely dependent on IL …

Infection with soil-transmitted helminths (STH) remains a major burden on global health and
agriculture. Our understanding of the immunological mechanisms that govern whether an …

RELMα is a small, secreted protein expressed by type 2 cytokine-activated “M2”
macrophages in helminth infection and allergy. At steady state and in response to type 2 …

The family of resistin-like molecules (RELMs) consists of four members in rodents
(RELMα/FIZZ1/HIMF, RELMβ/FIZZ2, Resistin/FIZZ3, and RELMγ/FIZZ4) and two members in …

Macrophages are a heterogeneous population of innate immune cells that are often divided
into two major subsets: classically activated, typically pro-inflammatory (M1) macrophages …

Diabetes-related ulcers and slow-healing wounds pose a significant health risk to
individuals due to their uncertain causes. Mortality rates for diabetes foot ulcers (DFUs) …

Introduction Intestinal roundworms cause chronic debilitating disease in animals, including
humans. Traditional experimental models of these types of infection use a large single-dose …