[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Polymeric nanoparticles for drug delivery: Recent developments and future prospects

B Begines, T Ortiz, M Pérez-Aranda, G Martínez… - Nanomaterials, 2020 - mdpi.com
The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led
to an increasing interest in the development and optimization of drug-delivery systems …

Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles

R De, MK Mahata, KT Kim - Advanced Science, 2022 - Wiley Online Library
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

[HTML][HTML] Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment

K Elumalai, S Srinivasan, A Shanmugam - Biomedical Technology, 2024 - Elsevier
This review evaluates the literature on nanoparticle-based drug delivery systems for cancer
treatment and assesses their efficacy. Nanoparticles have shown potential for improving …

Advances and limitations of drug delivery systems formulated as eye drops

C Jumelle, S Gholizadeh, N Annabi, R Dana - Journal of Controlled …, 2020 - Elsevier
Topical instillation of eye drops remains the most common and easiest route of ocular drug
administration, representing the treatment of choice for many ocular diseases. Nevertheless …

Novel drug delivery systems for the management of dry eye

N Nagai, H Otake - Advanced drug delivery reviews, 2022 - Elsevier
Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …

Nanotechnology for topical drug delivery to the anterior segment of the eye

A Vaneev, V Tikhomirova, N Chesnokova… - International journal of …, 2021 - mdpi.com
Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …

[HTML][HTML] Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties

A Subrizi, EM Del Amo, V Korzhikov-Vlakh… - Drug discovery today, 2019 - Elsevier
Highlights•Ocular drug delivery is a field in which regular ADME tools are not useful.•
Pharmacokinetics based dosing aid for ocular drug delivery is presented.•User-friendly …

Cyclosporine-loaded micelles for ocular delivery: Investigating the penetration mechanisms

M Ghezzi, I Ferraboschi, A Delledonne… - Journal of Controlled …, 2022 - Elsevier
Cyclosporine is an immunomodulatory drug commonly used for the treatment of mild-to-
severe dry eye syndrome as well as intermediate and posterior segment diseases as uveitis …