[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives
H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …
impairment and blindness globally. Drug administration through the topical ocular route is …
Polymeric nanoparticles for drug delivery: Recent developments and future prospects
B Begines, T Ortiz, M Pérez-Aranda, G Martínez… - Nanomaterials, 2020 - mdpi.com
The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led
to an increasing interest in the development and optimization of drug-delivery systems …
to an increasing interest in the development and optimization of drug-delivery systems …
Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …
[HTML][HTML] Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment
K Elumalai, S Srinivasan, A Shanmugam - Biomedical Technology, 2024 - Elsevier
This review evaluates the literature on nanoparticle-based drug delivery systems for cancer
treatment and assesses their efficacy. Nanoparticles have shown potential for improving …
treatment and assesses their efficacy. Nanoparticles have shown potential for improving …
Advances and limitations of drug delivery systems formulated as eye drops
Topical instillation of eye drops remains the most common and easiest route of ocular drug
administration, representing the treatment of choice for many ocular diseases. Nevertheless …
administration, representing the treatment of choice for many ocular diseases. Nevertheless …
Novel drug delivery systems for the management of dry eye
Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …
considerable research interest. Conventional therapy for DED involves the use of artificial …
Nanotechnology for topical drug delivery to the anterior segment of the eye
A Vaneev, V Tikhomirova, N Chesnokova… - International journal of …, 2021 - mdpi.com
Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …
the most prevalent drug form, especially for widely distributed anterior segment eye …
[HTML][HTML] Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties
A Subrizi, EM Del Amo, V Korzhikov-Vlakh… - Drug discovery today, 2019 - Elsevier
Highlights•Ocular drug delivery is a field in which regular ADME tools are not useful.•
Pharmacokinetics based dosing aid for ocular drug delivery is presented.•User-friendly …
Pharmacokinetics based dosing aid for ocular drug delivery is presented.•User-friendly …
Cyclosporine-loaded micelles for ocular delivery: Investigating the penetration mechanisms
M Ghezzi, I Ferraboschi, A Delledonne… - Journal of Controlled …, 2022 - Elsevier
Cyclosporine is an immunomodulatory drug commonly used for the treatment of mild-to-
severe dry eye syndrome as well as intermediate and posterior segment diseases as uveitis …
severe dry eye syndrome as well as intermediate and posterior segment diseases as uveitis …