Natural polysaccharides: Chemical properties and application in pharmaceutical formulations

M Tudu, A Samanta - European Polymer Journal, 2023 - Elsevier
Natural polysaccharides have an important role in pharmaceutical industries and are
considered a huge source and importance. Polysaccharides are biopolymers characterized …

Anticancer drugs: recent strategies to improve stability profile, pharmacokinetic and pharmacodynamic properties

G Ioele, M Chieffallo, MA Occhiuzzi, M De Luca… - Molecules, 2022 - mdpi.com
In past decades, anticancer research has led to remarkable results despite many of the
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …

Fabrication of self-healing pectin/chitosan hybrid hydrogel via Diels-Alder reactions for drug delivery with high swelling property, pH-responsiveness, and …

D Li, S Wang, Y Meng, Z Guo, M Cheng, J Li - Carbohydrate Polymers, 2021 - Elsevier
Self-healing hydrogels with pH-responsiveness could protect loaded drugs from being
destroyed till it arrives to the target. The pectin-based hydrogel is a candidate due to the …

Nanoparticulation of prodrug into medicines for cancer therapy

Y Zhang, H Cui, R Zhang, H Zhang… - Advanced …, 2021 - Wiley Online Library
This article provides a broad spectrum about the nanoprodrug fabrication advances co‐
driven by prodrug and nanotechnology development to potentiate cancer treatment. The …

Dietary fat and cancer—which is good, which is bad, and the body of evidence

B Bojková, PJ Winklewski… - International journal of …, 2020 - mdpi.com
A high-fat diet (HFD) induces changes in gut microbiota leading to activation of pro-
inflammatory pathways, and obesity, as a consequence of overnutrition, exacerbates …

The promise of nanotechnology in personalized medicine

MA Alghamdi, AN Fallica, N Virzì… - Journal of personalized …, 2022 - mdpi.com
Both personalized medicine and nanomedicine are new to medical practice. Nanomedicine
is an application of the advances of nanotechnology in medicine and is being integrated into …

A review of lignocellulosic-derived nanoparticles for drug delivery applications: lignin nanoparticles, xylan nanoparticles, and cellulose nanocrystals

CJ Wijaya, S Ismadji, S Gunawan - Molecules, 2021 - mdpi.com
Due to their biocompatibility, biodegradability, and non-toxicity, lignocellulosic-derived
nanoparticles are very potential materials for drug carriers in drug delivery applications …

Engineering of small-molecule lipidic prodrugs as novel nanomedicines for enhanced drug delivery

L Huang, J Yang, T Wang, J Gao, D Xu - Journal of Nanobiotechnology, 2022 - Springer
A widely established prodrug strategy can effectively optimize the unappealing properties of
therapeutic agents in cancer treatment. Among them, lipidic prodrugs extremely uplift the …

[HTML][HTML] Sustained and targeted delivery of hydrophilic drug compounds: A review of existing and novel technologies from bench to bedside

D Hawthorne, A Pannala, S Sandeman… - Journal of Drug Delivery …, 2022 - Elsevier
The sustained and/or targeted delivery of hydrophilic drugs is an important field within drug
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …

Recent trends in nanocarrier‐based targeted chemotherapy: selective delivery of anticancer drugs for effective lung, colon, cervical, and breast cancer treatment

KT Jin, ZB Lu, JY Chen, YY Liu, HR Lan… - Journal of …, 2020 - Wiley Online Library
Chemotherapy drugs are cytotoxic to tumor cells, but their lack of specificity leads to a range
of side effects. The off‐target effects of such drugs can be improved through the use of …