The epidemiology of Mayaro virus in the Americas: A systematic review and key parameter estimates for outbreak modelling

EY Caicedo, K Charniga, A Rueda… - PLoS neglected …, 2021 - journals.plos.org
Mayaro virus (MAYV) is an arbovirus that is endemic to tropical forests in Central and South
America, particularly within the Amazon basin. In recent years, concern has increased …

Epidemic alphaviruses: ecology, emergence and outbreaks

SR Azar, RK Campos, NA Bergren, VN Camargos… - Microorganisms, 2020 - mdpi.com
Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has
been a growing public health concern. In particular, agents from the genus Alphavirus pose …

Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope

AS Kim, NM Kafai, ES Winkler, TC Gilliland, EL Cottle… - Cell, 2021 - cell.com
Alphaviruses are emerging, mosquito-transmitted pathogens that cause musculoskeletal
and neurological disease in humans. Although neutralizing antibodies that inhibit individual …

Distinct cellular tropism and immune responses to alphavirus infection

NM Kafai, MS Diamond, JM Fox - Annual review of immunology, 2022 - annualreviews.org
Alphaviruses are emerging and reemerging viruses that cause disease syndromes ranging
from incapacitating arthritis to potentially fatal encephalitis. While infection by arthritogenic …

Chikungunya virus exposure partially cross-protects against Mayaro virus infection in mice

MJ Fumagalli, WM de Souza… - Journal of …, 2021 - Am Soc Microbiol
Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are closely related members of the
Semliki Forest virus antigenic complex classified as belonging to the genus Alphavirus of the …

Adenoviral-vectored Mayaro and Chikungunya virus vaccine candidates afford partial cross-protection from lethal challenge in A129 mouse model

RK Campos, L Preciado-Llanes, SR Azar… - Frontiers in …, 2020 - frontiersin.org
Mayaro (MAYV) and chikungunya viruses (CHIKV) are vector-borne arthritogenic
alphaviruses that cause acute febrile illnesses. CHIKV is widespread and has recently …

Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses

RJ Malonis, JT Earnest, AS Kim… - Proceedings of the …, 2021 - National Acad Sciences
Arthritogenic alphaviruses are globally distributed, mosquito-transmitted viruses that cause
rheumatological disease in humans and include Chikungunya virus (CHIKV), Mayaro virus …

Development of a next-generation chikungunya virus vaccine based on the HydroVax platform

DK Slifka, HP Raué, WC Weber, TF Andoh… - PLoS …, 2022 - journals.plos.org
Chikungunya virus (CHIKV) is an emerging/re-emerging mosquito-borne pathogen
responsible for explosive epidemics of febrile illness characterized by debilitating …

Implementation of in silico methods to predict common epitopes for vaccine development against Chikungunya and Mayaro viruses

H Hoque, R Islam, S Ghosh, MM Rahaman, NA Jewel… - Heliyon, 2021 - cell.com
Being a Positive sense RNA virus the recent reemergence of Chikungunya and Mayaro
virus has taken the concern of the leading scientific communities of the world. Though the …

A bivalent trans-amplifying RNA vaccine candidate induces potent chikungunya and ross river virus specific immune responses

C Schmidt, FD Hastert, J Gerbeth, T Beissert, U Sahin… - Vaccines, 2022 - mdpi.com
Alphaviruses such as the human pathogenic chikungunya virus (CHIKV) and Ross River
virus (RRV) can cause explosive outbreaks raising public health concerns. However, no …