A state-of-the-art review of experimental and computational studies of granular materials: properties, advances, challenges, and future directions

P Tahmasebi - Progress in Materials Science, 2023 - Elsevier
Modeling of heterogeneous materials and media is a problem of fundamental importance to
a wide class of phenomena and systems, ranging from condensed matter physics, soft …

A critical review on granulation of pharmaceuticals and excipients: Principle, analysis and typical applications

B Wang, X Sun, J Xiang, X Guo, Z Cheng, W Liu… - Powder Technology, 2022 - Elsevier
Solid dosage forms require the addition of different types of excipients such as flowability,
compressibility, disintegration, solubility, stability and other physical and chemical properties …

Modeling of inter-and intra-particle coating uniformity in a Wurster fluidized bed by a coupled CFD-DEM-Monte Carlo approach

Z Jiang, C Rieck, A Bück, E Tsotsas - Chemical Engineering Science, 2020 - Elsevier
Abstract A coupled CFD-DEM and Monte Carlo approach was developed to investigate
coating properties in a Wurster fluidized bed by considering gas flow, particle motion, droplet …

Experimental characterization of the effect of liquid viscosity on collisions between a multi-component droplet and a heated particle

L Shao, D Liu, J Ma, X Chen - Chemical Engineering Science, 2022 - Elsevier
Understanding droplet-particle collisions is critical for regulating spray coating processes.
Existing studies mainly focused on collision between a single component droplet and a …

Quality by design for wet granulation in pharmaceutical processing: assessing models for a priori design and scaling

D Kayrak-Talay, S Dale, C Wassgren, J Litster - Powder technology, 2013 - Elsevier
The effective implementation of Quality by Design (QbD) for wet granulation requires
quantitative models for design and scaling of granulators. This paper reviews that current …

Three dimensional characterization of morphology and internal structure of soft material agglomerates produced in spray fluidized bed by X-ray tomography

R Pashminehazar, A Kharaghani, E Tsotsas - Powder Technology, 2016 - Elsevier
Food powders such as maltodextrin are often produced in agglomerate form in spray
fluidized beds in order to enhance their user properties. These agglomerates mostly have …

Improving acoustic agglomeration efficiency of coal-fired fly-ash particles by addition of liquid binders

G Zhang, TT Zhou, L Zhang, J Wang, Z Chi… - Chemical Engineering …, 2018 - Elsevier
Acoustic agglomeration is an efficient pretreatment technology for industrial flue gases,
which can significantly improve their removal efficiency of conventional dust filters that …

PTV experiments and DEM simulations of the coefficient of restitution for irregular particles impacting on horizontal substrates

Z Jiang, J Du, C Rieck, A Bück, E Tsotsas - Powder Technology, 2020 - Elsevier
For systems of particles with irregular shapes, the collisions between particles and between
particles and walls are highly complex and strongly related to the contact geometry. In this …

Characterization of the internal morphology of agglomerates produced in a spray fluidized bed by X-ray tomography

M Dadkhah, M Peglow, E Tsotsas - Powder Technology, 2012 - Elsevier
The internal structure of granules produced by spray fluidized bed agglomeration was
investigated by means of X-ray micro-computer-tomography. The X-ray tomography delivers …

CFD–DEM study of residence time, droplet deposition, and collision velocity for a binary particle mixture in a Wurster fluidized bed coater

Z Jiang, A Bück, E Tsotsas - Drying Technology, 2018 - Taylor & Francis
An approach that combines computational fluid dynamics with the discrete element method
is applied to investigate the residence time and collision velocity in different processing …