[HTML][HTML] Blood-based biomarkers of cerebral small vessel disease

LY Wu, YL Chai, IK Cheah, RSL Chia, S Hilal… - Ageing Research …, 2024 - Elsevier
Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …

Brain vascular health in ALS is mediated through motor cortex microvascular integrity

S Schreiber, J Bernal, P Arndt, F Schreiber, P Müller… - Cells, 2023 - mdpi.com
Brain vascular health appears to be critical for preventing the development of amyotrophic
lateral sclerosis (ALS) and slowing its progression. ALS patients often demonstrate …

Modeling venous bias in resting state functional MRI metrics

J Huck, AT Jäger, U Schneider, S Grahl… - Human Brain …, 2023 - Wiley Online Library
Resting‐state (rs) functional magnetic resonance imaging (fMRI) is used to detect low‐
frequency fluctuations in the blood oxygen‐level dependent (BOLD) signal across brain …

Deep learning for 3D vascular segmentation in hierarchical phase contrast tomography: a case study on kidney

E Yagis, S Aslani, Y Jain, Y Zhou, S Rahmani… - Scientific Reports, 2024 - nature.com
Automated blood vessel segmentation is critical for biomedical image analysis, as vessel
morphology changes are associated with numerous pathologies. Still, precise segmentation …

Computational modeling of multiscale collateral blood supply in a whole-brain-scale arterial network

T Otani, N Nishimura, H Yamashita, S Ii… - PLOS Computational …, 2023 - journals.plos.org
The cerebral arterial network covering the brain cortex has multiscale anastomosis
structures with sparse intermediate anastomoses (O [102] μm in diameter) and dense pial …

Multi-scale multi-physics model of brain interstitial water flux by transcranial Direct Current Stimulation

N Khadka, C Poon, LM Cancel… - Journal of neural …, 2023 - iopscience.iop.org
Objective. Transcranial direct current stimulation (tDCS) generates sustained electric fields
in the brain, that may be amplified when crossing capillary walls (across blood-brain barrier …

Non-invasive flow mapping of parasagittal meningeal lymphatics using 2D interslice flow saturation MRI

JH Kim, RE Yoo, SH Choi, SH Park - Fluids and Barriers of the CNS, 2023 - Springer
The clearance pathways of brain waste products in humans are still under debate in part
due to the lack of noninvasive imaging techniques for meningeal lymphatic vessels (mLVs) …

Flow reduction due to arterial catheterization during stroke treatment–A computational study using a distributed compartment model

A Pradhan, F Mut, M Sosale… - International Journal for …, 2024 - Wiley Online Library
The effectiveness of various stroke treatments depends on the anatomical variability of the
cerebral vasculature, particularly the collateral blood vessel network. Collaterals at the level …

Segmentation of supragranular and infragranular layers in ultra-high-resolution 7T ex vivo MRI of the human cerebral cortex

X Zeng, O Puonti, A Sayeed, R Herisse, J Mora… - Cerebral …, 2024 - academic.oup.com
Accurate labeling of specific layers in the human cerebral cortex is crucial for advancing our
understanding of neurodevelopmental and neurodegenerative disorders. Building on recent …

Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging–A Symposium Review

JK Marchant, NG Ferris, D Grass, MS Allen… - Neuroinformatics, 2024 - Springer
Advances in the spatiotemporal resolution and field-of-view of neuroimaging tools are
driving mesoscale studies for translational neuroscience. On October 10, 2023, the Center …