The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …

Colorectal cancer (CRC) is a malignant tumor in the digestive system whose incidence and
mortality is high-ranking among tumors worldwide. The initiation and progression of CRC is …

Cancers are able to grow by subverting immune suppressive pathways, to prevent the
malignant cells as being recognized as dangerous or foreign. This mechanism prevents the …

Tumor recurrence years after seemingly successful treatment of primary tumors is one of the
major causes of mortality in patients with cancer. Reactivation of dormant tumor cells is …

Inflammation is associated with the development and malignant progression of most
cancers. As most of the cell types involved in cancer-associated inflammation are genetically …

Tumor-associated macrophages (TAMs) expressing the multi-ligand endocytic receptor
mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis …

S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca2+ homeostasis …

The tumor microenvironment (TME) is a hypoxic, acidic, and immune/inflammatory cell–
enriched milieu that plays crucial roles in tumor development, growth, progression, and …

Prostate cancer is the most commonly diagnosed cancer and the second leading cause of
cancer-related death among men in western countries. Androgen deprivation therapy (ADT) …

Survivin is an anti-apoptotic protein that is highly expressed in many cancers, including
malignant gliomas. Preclinical studies established that the conjugated survivin peptide …