Homocysteine–from disease biomarker to disease prevention
AD Smith, H Refsum - Journal of internal medicine, 2021 - Wiley Online Library
We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …
that are associated with raised concentrations of plasma total homocysteine. The …
Homocysteine, B vitamins, and cognitive impairment
AD Smith, H Refsum - Annual review of nutrition, 2016 - annualreviews.org
Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …
Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements–a systematic review
Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …
Vitamin B12, folic acid, and the nervous system
E Reynolds - The lancet neurology, 2006 - thelancet.com
There are many reasons for reviewing the neurology of vitamin-B12 and folic-acid
deficiencies together, including the intimate relation between the metabolism of the two …
deficiencies together, including the intimate relation between the metabolism of the two …
Facts and recommendations about total homocysteine determinations: an expert opinion
Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …
methods have been introduced. A wide range of disorders are associated with increased …
[HTML][HTML] Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia
R Obeid, W Herrmann - FEBS letters, 2006 - Elsevier
Mild to moderate hyperhomocysteinemia is a risk factor for neurodegenerative diseases.
Human studies suggest that homocysteine (Hcy) plays a role in brain damage, cognitive and …
Human studies suggest that homocysteine (Hcy) plays a role in brain damage, cognitive and …
N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility
S Dodd, O Dean, DL Copolov, GS Malhi… - Expert opinion on …, 2008 - Taylor & Francis
Background: Glutathione is an endogenous antioxidant and has a ubiquitous role in many of
the body's defences. Treatment with N-acetylcysteine (NAC) has been shown to increase …
the body's defences. Treatment with N-acetylcysteine (NAC) has been shown to increase …
Mechanistic link between vitamin B12 and Alzheimer's disease
Alzheimer's disease (AD) is the most common form of dementia in the elderly population,
affecting over 55 million people worldwide. Histopathological hallmarks of this multifactorial …
affecting over 55 million people worldwide. Histopathological hallmarks of this multifactorial …
[HTML][HTML] Homocysteine and folate as risk factors for dementia and Alzheimer disease
G Ravaglia, P Forti, F Maioli, M Martelli… - The American journal of …, 2005 - Elsevier
Background: In cross-sectional studies, elevated plasma total homocysteine (tHcy)
concentrations have been associated with cognitive impairment and dementia. Incidence …
concentrations have been associated with cognitive impairment and dementia. Incidence …
[HTML][HTML] High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study
KL Tucker, N Qiao, T Scott, I Rosenberg… - The American journal of …, 2005 - Elsevier
Background: Elevated homocysteine concentrations may contribute to cognitive impairment.
Most elevations in homocysteine result from inadequate folate, vitamin B-12, or vitamin B-6 …
Most elevations in homocysteine result from inadequate folate, vitamin B-12, or vitamin B-6 …