Education and training to enhance end-of-life care for nursing home staff: a systematic literature review
Background The delivery of end-of-life care in nursing homes is challenging. This situation is
of concern as 20% of the population die in this setting. Commonly reported reasons include …
of concern as 20% of the population die in this setting. Commonly reported reasons include …
Acute diarrhea in children
N Radlović, Z Leković, B Vuletić… - Srpski arhiv za …, 2015 - doiserbia.nb.rs
Acute diarrhea (AD) is the most frequent gastroenterological disorder, and the main cause of
dehydration in childhood. It is manifested by a sudden occurrence of three or more watery or …
dehydration in childhood. It is manifested by a sudden occurrence of three or more watery or …
An under-represented and underserved population in trials: methodological, structural, and systemic barriers to the inclusion of adults lacking capacity to consent
V Shepherd - Trials, 2020 - Springer
Background There is increasing international recognition that populations included in trials
should adequately represent the population treated in clinical practice; however, adults who …
should adequately represent the population treated in clinical practice; however, adults who …
Incidence and antibiotic prescribing for clinically diagnosed urinary tract infection in older adults in UK primary care, 2004-2014
H Ahmed, D Farewell, HM Jones, NA Francis… - PloS one, 2018 - journals.plos.org
Urinary tract infections (UTI) are an important cause of morbidity and antibiotic use in older
adults but there are little data describing disease burden in primary care. The aim of this …
adults but there are little data describing disease burden in primary care. The aim of this …
Protection by exclusion? The (lack of) inclusion of adults who lack capacity to consent to research in clinical trials in the UK
V Shepherd, F Wood, R Griffith, M Sheehan, K Hood - Trials, 2019 - Springer
Background Around two million adults in the UK have significantly impaired decision-making
capacity. However, there are concerns that this population is under-represented in research …
capacity. However, there are concerns that this population is under-represented in research …
Early use of probiotics might prevent antibiotic-associated diarrhea in elderly (> 65 years): a systematic review and meta-analysis
L Zhang, X Zeng, D Guo, Y Zou, H Gan, X Huang - BMC geriatrics, 2022 - Springer
Background Antibiotic-associated diarrhea (AAD) is diarrhea associated with consuming
antibiotics that cannot be explained by other causes. AAD prolongs admission time and …
antibiotics that cannot be explained by other causes. AAD prolongs admission time and …
Unpacking the 'black box of horrendousness': a qualitative exploration of the barriers and facilitators to conducting trials involving adults lacking capacity to consent
V Shepherd, K Hood, F Wood - Trials, 2022 - Springer
Background Trials involving adults who lack capacity to consent encounter a range of ethical
and methodological challenges, resulting in these populations frequently being excluded …
and methodological challenges, resulting in these populations frequently being excluded …
Research involving adults lacking capacity to consent: the impact of research regulation on 'evidence biased' medicine
V Shepherd - BMC Medical Ethics, 2016 - Springer
Background Society is failing in its moral obligation to improve the standard of healthcare
provided to vulnerable populations, such as people who lack decision making capacity, by a …
provided to vulnerable populations, such as people who lack decision making capacity, by a …
Setting up a clinical trial in care homes: challenges encountered and recommendations for future research practice
V Shepherd, J Nuttall, K Hood, CC Butler - BMC research notes, 2015 - Springer
Background Older adults in care homes have increasingly complex health care needs, and
care provision should be evidence-based whenever possible. However, recruitment of frail …
care provision should be evidence-based whenever possible. However, recruitment of frail …
Probiotics use for antibiotic-associated diarrhea: a pragmatic participatory evaluation in nursing homes
HA van Wietmarschen, M Busch, A van Oostveen… - BMC …, 2020 - Springer
Background Antibiotic-associated diarrhea (AAD) occurs in 2–25% of nursing home
residents, which may lead to dehydration, malnutrition, severe complications and …
residents, which may lead to dehydration, malnutrition, severe complications and …